전립선비대증 환자에서 조직 내 세균감염의 의미
Clinical Significance of Infected Prostate Tissue in Patients with Benign Prostatic Hyperplasia
최훈, 박승철, 조지현, 정희종,
소속 상세정보
최훈 ( Choi Hoon )
원광대학교 의과대학 비뇨기과학교실
박승철 ( Park Seung-Chol )
원광대학교 의과대학 비뇨기과학교실
조지현 ( Cho Ji-Hyun )
원광대학교 의과대학 진단검사의학교실
정희종 ( Jeong Hee-Jong )
원광대학교 의과대학 비뇨기과학교실
KMID : 0358320090500101014
Abstract
Purpose:Benign prostatic hyperplasia (BPH) and prostatitis are the most common benign diseases of the prostate gland and over time affect a significant majority of men. We evaluated the relation between BPH and infection in prostatic tissue in men who underwent transurethral resection of the prostate (TURP).
Materials and Methods:This prospective study included 63 consecutive patients diagnosed with BPH and scheduled for TURP. During the TURP, 1-2 g chips were collected after resection of the prostatic urethra, and specimens were transported to the laboratory in sterile saline. Homogenized specimens were incubated for 7 days. The patients were divided into 2 groups (group 1: culture positive, group 2: culture negative). We compared prostate volume, prostate calculi, serum prostate-specific antigen (PSA), International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), post-void residual urine, and ratio of the transitional zone prostate to total prostate (transitional zone ratio).
Results: Mean age was 72 years and mean serum PSA was 4.36 ng/dl. Group 1 included 7 patients (11.1%) and group 2 included 57 patients (88.9%). There were no significant differences in prostate volume, prostate calculi, serum PSA, IPSS, Qmax, or post-void residual urine between groups, but the transitional zone ratio was higher in group 1 (45.4%) than in group 2 (30.3%) (p＜0.05).
Conclusions: About 11% of the prostate tissue cultures showed bacterial growth. The transitional zone ratio was higher in patients with bacteria growth. Bacterial infection may be related to benign prostatic hyperplasia. (Korean J Urol 2009;50:1014-1017)
키워드
Prostatic hyperplasia;Prostatitis;Inflammation
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