Alpha-Methylacyl-Coenzyme A Racemase-Expressing Urachal Adenocarcinoma of the Abdominal Wall
하윤석, 김용준, 이상철, 김원재, 이옥준, 김영원, 윤석중, 민병달,
소속 상세정보
하윤석 ( Ha Yun-Sok )
Chungbuk National University
김용준 ( Kim Yong-June )
Chungbuk National University
이상철 ( Lee Sang-Cheol )
Chungbuk National University
김원재 ( Kim Wun-Jae )
Chungbuk National University
이옥준 ( Lee Ok-Jun )
충북대학교 의과대학 병리학교실
김영원 ( Kim Young-Won )
Chungbuk National University
윤석중 ( Yun Seok-Joong )
Chungbuk National University
민병달 ( Min Byung-Dal )
Chungbuk National University
KMID : 0358320100510070498
Abstract
Urachal adenocarcinomas are very rare and about one third of these neoplasms arise in urachal remnants. To demonstrate the origin of the urachal adenocarcinoma is not easy, but it is very important for managing patient care. We report on a 35-year-old man who complained of a palpable mass in the periumbilical area. The mass was incidentally identified 10 days earlier. Computed tomography revealed a well-defined enhancing mass with internal calcification and septation abutting on the dome of the urinary bladder. The clinical diagnosis was urachal cancer, which seemed to invade the urinary bladder. Thus, we performed mass excision and partial resection of the bladder. Histopathologically, the mass was diagnosed as mucinous cystadenocarcinoma originating from urachal remnants that showed an unusual expression of alpha-methylacyl-coenzyme A racemase (AMACR). To our knowledge, this report is the first case of AMACR-expressing urachal adenocarcinoma arising in the abdominal wall.
키워드
Alpha-methylacyl-CoA racemase;Biological markers;Cystadenocarcinoma;mucinous;Urachus
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