Sarcomatoid Carcinoma of the Urinary Bladder: A Clinicopathological Study of 4 Cases and a Review of the Literature
Stamatiou Konstantinos, Galariotis Nikolaos, Michailidis Ioannis, Petrakopoulou Nerantzoula, Moustou Helen, Zizi-Sermpetzoglou Adamantia,
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( Stamatiou Konstantinos )
Greece Tzaneio General Hospital of Pireas Departments of Urology
( Galariotis Nikolaos )
Greece Tzaneio General Hospital of Pireas Departments of Urology
( Michailidis Ioannis )
Greece Tzaneio General Hospital of Pireas Departments of Urology
( Petrakopoulou Nerantzoula )
Greece Tzaneio General Hospital of Pireas Pathology
( Moustou Helen )
Greece Tzaneio General Hospital of Pireas Pathology
( Zizi-Sermpetzoglou Adamantia )
Greece Tzaneio General Hospital of Pireas Pathology
KMID : 0358320100510100724
Abstract
Sarcomatoid carcinoma (SC) of urinary bladder is a rare tumor exhibiting aggressive behavior. Here we are reviewing the pathologic and clinical characteristics of 4 consecutive cases of this rare tumor. Three out of 4 patients were males and one female. The median age was 72.8 years (range, 60-79 years). Patients underwent transurethral resection of bladder tumor and the diagnosis of bladder SC was established on the pathologic examination of the resected bladder tissue. Despite treatment all patients died within 22 months of the diagnosis of SC. SC of the bladder are true biphasic malignant neoplasm exhibiting morphologic and immunohistochemical evidence of epithelial and mesenchymal differentiation with the presence or absence of heterologous elements. The aggressive of the tumor precludes radical therapy whenever possible, since adjuvant therapy seems to have little effect.
키워드
Transitional cell carcinoma;Urinary bladder neoplasms
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