Correlation between Serum Total Testosterone and the AMS and IIEF Questionnaires in Patients with Erectile Dysfunction with Testosterone Deficiency Syndrome
강재일, 함병국, 오미미, 김제종, 문두건,
소속 상세정보
강재일 ( Kang Jae-Il )
Korea University Medical Center Department of Urology
함병국 ( Ham Byeong-Kuk )
Korea University Medical Center Department of Urology
오미미 ( Oh Mi-Mi )
Korea University Medical Center Department of Urology
김제종 ( Kim Je-Jong )
Korea University Medical Center Department of Urology
문두건 ( Moon Du-Geon )
Korea University Medical Center Department of Urology
KMID : 0358320110520060416
Abstract
Purpose: This study was conducted to investigate the relationship between serum total testosterone levels and scores on the Aging Male’s Symptom (AMS) scale and the International Index of Erectile Function (IIEF) in men with erectile dysfunction with testosterone deficiency syndrome (TDS).
Materials and Methods: From January 2005 to July 2008, 134 patients who complained of sexual dysfunction such as erectile dysfunction or decreased libido as the main symptoms of TDS with serum total testosterone levels less than 3.5 ng/ml were evaluated by independent t-test and linear regression analysis, respectively. Patients with treated hypogonadism within 6 months, with a history of taking a PDE5 inhibitor or an antidepressant for a depressive disorder, or who had metabolic syndrome were excluded from this study.
Results: The AMS scale and its 3 subdomain scores were not significantly correlated with the total testosterone level. By contrast, the total IIEF score and the score of each IIEF domain except sexual desire showed a weakly significantly positive correlation with serum total testosterone.
Conclusions: In TDS patients with erectile dysfunction, there was a low relationship between serum total testosterone levels and the AMS scale and a weakly positive correlation between total testosterone levels and all IIEF domains except sexual desire. There was a low relationship between the AMS scale, the sexual desire domain score of the IIEF, and total testosterone. We should understand these limitations when evaluating patients with erectile dysfunction with TDS. New scales should be developed for the evaluation of erectile dysfunction in these patients.
키워드
Erectile dysfunction; Questionnaires; Testosterone
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