Interval from Prostate Biopsy to Robot-Assisted Laparoscopic Radical Prostatectomy (RALP): Effects on Surgical Difficulties
김인성, Na Woong, 남정수, 오종진, 정창욱, 홍성규, 변석수, 이상은,
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김인성 ( Kim In-Sung )
Seoul National University College of Medicine Department of Urology
( Na Woong )
Seoul National University Bundang Hospital Department of Urology
남정수 ( Nam Jung-Su )
Seoul National University Bundang Hospital Department of Urology
오종진 ( Oh Jong-Jin )
Seoul National University Bundang Hospital Department of Urology
정창욱 ( Jeong Chang-Wook )
Seoul National University Bundang Hospital Department of Urology
홍성규 ( Hong Sung-Kyu )
Seoul National University Bundang Hospital Department of Urology
변석수 ( Byun Seok-Soo )
Seoul National University Bundang Hospital Department of Urology
이상은 ( Lee Sang-Eun )
Seoul National University Bundang Hospital Department of Urology
KMID : 0358320110520100664
Abstract
Purpose:Traditionally, an interval of 4 to 6 weeks has been recommended after prostate biopsy before open radical prostatectomy. However, such an interval is not explicitly specified in robot-assisted laparoscopic radical prostatectomy (RALP). This study was designed to determine whether the interval from prostate biopsy to RALP affects surgical difficulties.
Materials and Methods :Between January 2008 and May 2009, a total of 237 men underwent RALP in our institution. The interval from biopsy to RALP was categorized as follows: ≤ 2 weeks, >2 to ≤ 4 weeks, >4 to ≤ 6 weeks, >6 to ≤ 8 weeks, and >8 weeks. Multivariate analysis was used to identify whether the interval from prostate biopsy to RALP was an independent predictor of operative time, estimated blood loss (EBL), margin positivity, continence, and potency.
Results:Among the 5 groups, there were no significant differences in age, body mass index (BMI), preoperative serum prostate-specific antigen (PSA), prostate volume, or preoperative International Index of Erectile Dysfunction-5 score (all p>0.05). In the multivariate analysis, operative time was significantly associated with prostate volume. EBL was associated with prostate volume and BMI. Margin positivity was associated with preoperative serum PSA, prostate volume, and biopsy Gleason score. Postoperative continence and potency were significantly associated with age. However, in univariate and multivariate analyses, the interval from biopsy to RALP was not significantly associated with operative time, EBL, margin positivity, postoperative continence, or potency (all p>0.05).
Conclusions:Our data suggest that the interval from prostate biopsy to RALP is not related to surgical difficulties.
키워드
Prostate biopsy; Prostate neoplasms; Robot-assisted prostatectomy
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