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Prevalence and Correlates of Nocturia in Community-dwelling Older Men: Results from the Korean Longitudinal Study on Health and Aging

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ÀÌ¿µÁÖ ( Lee Young-Ju ) 
Seoul National University College of Medicine Department of Urology

Á¤¼ºÁø ( Jeong Seong-Jin ) 
Seoul National University Bundang Hospital Department of Urology
º¯¼®¼ö ( Byun Seok-Soo ) 
Seoul National University Bundang Hospital Department of Urology
ÀÌÁ¤Àç ( Lee Jung-Jae ) 
Kyungpook National University College of Medicine Department of Psychiatry
ÇÑÁö¿ø ( Han Ji-Won ) 
Seoul National University Bundang Hospital Department of Neuropsychiatry
±è±â¿õ ( Kim Ki-Woong ) 
Seoul National University Bundang Hospital Department of Neuropsychiatry

Abstract


Purpose: To determine the prevalence and correlates of nocturia in Korean community-dwelling older men.

Materials and Methods: A study population of 439 Korean elderly men (¡Ã65 years of age, including 299 men from a randomly sampled population) was sampled from residents of Seongnam, Korea. Standardized face-to-face interviews and questionnaires were performed. In-person interviews solicited sociodemographic information, medical history, Mini-Mental State Examination (MMSE) score, and measurement of body mass index. Transrectal ultrasonography and laboratory tests including urinalysis and measurement of creatinine and prostate-specific antigen were performed. For the analysis of prevalence, 299 randomly sampled men were included. Men who answered the International Prostate Symptom Score questionnaire (n=424) were included in the analysis of the correlates of nocturia. Nocturia was defined as having to get up to urinate two or more times per night (¡Ã2).

Results: The overall prevalence of nocturia was 56.0% for community-dwelling older men. There was a significant correlation between age and the prevalence of nocturia (p<0.001). The univariate analysis revealed a significant association between nocturia and MMSE score (odds ratio [OR], 0.88; p<0.001), history of benign prostatic hyperplasia (BPH) (OR, 2.85; p=0.003), alpha-blocker usage (OR, 2.79; p=0.018), alcohol consumption (OR, 0.65; p=0.035), and smoking (OR, 0.58; p=0.025). Age, duration of education, MMSE score, and prostate volume were also significantly associated with nocturia. In the multivariate regression analysis using forward elimination, nocturia was significantly associated with a history of BPH and MMSE score.

Conclusions: The prevalence of nocturia was 56.0% in Korean community-dwelling older men. Nocturia was associated with age and a history of BPH. MMSE score was protective.

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Aged; Aged; 80 and over; Nocturia; Prevalence

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