High-Grade Prostatic Intraepithelial Neoplasia
Klink Joseph C, Miocinovic Ranko, Galluzzi Cristina Magi, Klein Eric A,
소속 상세정보
( Klink Joseph C )
Glickman Urologic and Kidney Institute
( Miocinovic Ranko )
Glickman Urologic and Kidney Institute
( Galluzzi Cristina Magi )
Glickman Urologic and Kidney Institute
( Klein Eric A )
Glickman Urologic and Kidney Institute
KMID : 0358320120530050297
Abstract
High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular signatures with prostate cancer. Its predictive value for the development of future adenocarcinoma during the prostate-specific antigen screening era has decreased, mostly owing to the increase in prostate biopsy cores. Nevertheless, a literature review supports that large-volume HGPIN and multiple cores of involvement at the initial biopsy should prompt a repeat biopsy of the prostate within 1 year. No treatment is recommended for HGPIN to slow its progression to cancer.
키워드
HGPIN; High grade prostatic intraepithelial neoplasia; Prostate biopsy; Prostate cancer
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