Surgical Experience with Retroperitoneal Liposarcoma in a Single Korean Tertiary Medical Center
나준채, 최경화, 양승철, 한웅규,
소속 상세정보
나준채 ( Na Joon-Chae )
Yonsei University Health System Urological Science Institute Department of Urology
최경화 ( Choi Kyung-Hwa )
Yonsei University Health System Urological Science Institute Department of Urology
양승철 ( Yang Seung-Choul )
Yonsei University Health System Urological Science Institute Department of Urology
한웅규 ( Han Woong-Kyu )
Yonsei University Health System Urological Science Institute Department of Urology
KMID : 0358320120530050310
Abstract
Purpose: This is a report of the surgical treatment and prognosis of retroperitoneal liposarcoma (RPLS) in Koreans.
Materials and Methods: Nineteen patients treated for RPLS between July 1, 1984, and March 31, 2009, were included. Patient demographics, histopathologic subtypes, survival rate, disease recurrence rate and interval, and adjuvant therapy were reviewed and analyzed.
Results: Of the 19 patients diagnosed with RPLS, 26.3% presented with well-differentiated RPLS, 10.5% with dedifferentiated RPLS, 15.8% with myxoid/round cell type, and 47.4% with mixed-type liposarcoma. The mean follow-up period was 66.8 months (range, 6 to 165 months). Primary RPLS was treated in 17 patients. Nine patients (52.9%) had recurrent disease, and recurrence developed at a mean of 47.7 months after primary or repeated surgical treatment. The overall survival rate was 84.2% during a mean follow-up of 66.8 months. The 3- and 5-year survival rates were 86.9%, and the 10-year survival rate was 69.5%. The recurrence interval was significantly shorter in recurrent RPLS cases (p=0.023). The mean growth rate of locally recurrent tumors was 0.34 cm per month.
Conclusions: The survival rates reported here were higher than in previous studies. Locally recurrent tumors presented with a low growth rate, which may have contributed to the relatively high survival rate. A high prevalence of mixed-type RPLS was also noted, and its cause and prognosis require further research.
키워드
Follow-up studies; Liposarcoma; Retroperitoneal liposarcoma; Retroperitoneal neoplasms; Sarcoma
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