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Prevalence and Clinical Features of Detrusor Underactivity among Elderly with Lower Urinary Tract Symptoms: A Comparison between Men and Women

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Á¤¼ºÁø ( Jeong Seong-Jin ) 
Seoul National University Bundang Hospital Department of Urology

±èÇöÁØ ( Kim Hyeon-June ) 
Seoul National University Bundang Hospital Department of Urology
ÀÌ¿µÁÖ ( Lee Young-Ju ) 
Seoul National University Bundang Hospital Department of Urology
ÀÌÁ¤±Ù ( Lee Jeong-Keun ) 
Seoul National University Bundang Hospital Department of Urology
À̺´±â ( Lee Byung-Ki ) 
Seoul National University Bundang Hospital Department of Urology
ÁÖ¿µ¹Î ( Choo Young-Min ) 
Seoul National University Bundang Hospital Department of Urology
¿ÀÁ¾Áø ( Oh Jong-Jin ) 
Seoul National University Bundang Hospital Department of Urology
ÀÌ»óö ( Lee Sang-Cheol ) 
Seoul National University Bundang Hospital Department of Urology
Á¤Ã¢¿í ( Jeong Chang-Wook ) 
Seoul National University Bundang Hospital Department of Urology
À±Ã¶¿ë ( Yoon Cheol-Yong ) 
Seoul National University Bundang Hospital Department of Urology
È«¼º±Ô ( Hong Sung-Kyu ) 
Seoul National University Bundang Hospital Department of Urology
º¯¼®¼ö ( Byun Seok-Soo ) 
Seoul National University Bundang Hospital Department of Urology
ÀÌ»óÀº ( Lee Sang-Eun ) 
Seoul National University Bundang Hospital Department of Urology

Abstract


Purpose: To identify the prevalence and clinical features of detrusor underactivity (DU) in elderly men and women presenting with lower urinary tract symptoms (LUTS).

Materials and Methods: We reviewed 1,179 patients aged over 65 years who had undergone a urodynamic study for LUTS with no neurological or anatomical conditions. DU was defined as a bladder contractility index <100 and a maximal flow rate (Qmax) ¡Â12 ml/s combined with a detrusor pressure at Qmax ¡Â10 cmH2O for men and women, respectively.

Results: Of the patients, 40.2% of men and 13.3% of women were classified as having DU (p<0.001). Types of clinical symptoms were not significantly different between patients with and without DU. In men, whereas the prevalence of bladder outlet obstruction (BOO) was constant across the age spectrum, the prevalence of DU and detrusor overactivity (DO) increased with age, and 46.5% of men with DU also had DO or BOO. In women, the prevalence of DU also increased with age, and the trend was more remarkable in women aged over 70 years. DU was accompanied by DO or urodynamic stress urinary incontinence (USUI) in 72.6% of the women with DU. Women with DU were found to have lower cystometric capacity and exhibited a greater incidence of reduced compliance than did women without DU.

Conclusions: DU was a common mechanism underlying LUTS in the elderly population, especially in men. One half of the men and three quarters of the women with DU also had other pathologies such as DO, BOO, or USUI.

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Aged; Prevalence; Urinary bladder; Urination disorders; Urodynamics

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