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Lung Metastasis of Ta Bladder Cancer: A Case Report and Literature Review

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Sano Takeshi, Haitani Takao, Kajita Yoichiro, Shichiri Yasumasa, Hamada Shinshichi, Nakashima Masakazu,
¼Ò¼Ó »ó¼¼Á¤º¸
 ( Sano Takeshi ) 
Otsu Municipal Hospital Department of Urology

 ( Haitani Takao ) 
Otsu Municipal Hospital Department of Urology
 ( Kajita Yoichiro ) 
Otsu Municipal Hospital Department of Urology
 ( Shichiri Yasumasa ) 
Otsu Municipal Hospital Department of Urology
 ( Hamada Shinshichi ) 
Otsu Municipal Hospital Department of Pathology
 ( Nakashima Masakazu ) 
Kyoto University Graduate School of Medicine Department of Urology

Abstract


A 66-year-old man with a history of multiple transurethral resections for recurrent bladder tumors, staged as Ta according to the International Union Against Cancer staging guidelines, presented with a complaint of dry cough. A round nodule with a diameter of 7.5 cm was detected in the lung by chest computed tomography, and a video-assisted thoracoscopic lobectomy was performed. Pulmonary metastasis of recurrent bladder cancer was diagnosed by immunohistochemistry staining for the urothelium-specific protein uroplakin Ia. Subsequently, 2 cycles of systemic chemotherapy were administered. Two and a half years after treatment, no recurrence of pulmonary lesions has been detected. A combination of complete resection of pulmonary lesions and systemic chemotherapy may result in a good prognosis for patients with non-muscle-invasive bladder cancer.

Å°¿öµå

Indirect fluorescent antibody technique;Solitary pulmonary nodule;Urinary bladder neoplasms

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