Hospitalization Decreases Serum Prostate-Specific Antigen Values Compared With Outpatient Values in Patients With Benign Prostatic Diseases
Yoon In-Seok, 신태영, 김선일, Park Seong-Kon, 장현익, 최종보, 안현수, 김용수, 김세중,
소속 상세정보
( Yoon In-Seok )
Ajou University School of Medicine Department of Urology
신태영 ( Shin Tae-Young )
Hallym University College of Medicine Department of Urology
김선일 ( Kim Sun-Il )
Ajou University School of Medicine Department of Urology
( Park Seong-Kon )
Ajou University School of Medicine Department of Urology
장현익 ( Jang Hyun-Ik )
Ajou University School of Medicine Department of Urology
최종보 ( Choi Jong-Bo )
Ajou University School of Medicine Department of Urology
안현수 ( Ahn Hyun-Soo )
Ajou University School of Medicine Department of Urology
김용수 ( Kim Young-Soo )
Ajou University School of Medicine Department of Urology
김세중 ( Kim Se-Joong )
Ajou University School of Medicine Department of Urology
KMID : 0358320130540090593
Abstract
Purpose: To investigate whether hospitalization influences serum prostate-specific antigen (PSA) values. Materials and Methods: Transrectal ultrasound-guided prostate biopsies were performed for detecting prostate cancer in 2,017 patients between February 2001 and April 2011 at Ajou University Hospital. Of those patients, 416 patients who were hospitalized for prostate biopsies, whose serum PSA values were measured at the outpatient department within 1 month of admission and also just after admission, and who had negative prostate biopsy results were included in the present study. We retrospectively reviewed the data of the 416 patients and compared the serum PSA values measured in the outpatient department with those measured during hospitalization. Results: Among all 416 patients, the interval between the two PSA measurements was 22.2 days (range, 3 to 30 days) and the prostate size measured by transrectal ultrasonography was 53.63 mL (range, 12.8 to 197.9 mL). Among all patients, mean serum PSA levels measured during hospitalization were significantly lower than those measured in the outpatient department (6.69 ng/mL vs. 8.01 ng/mL, p<0.001). When stratified according to age, the presence or absence of chronic prostatitis in the biopsy pathology, serum PSA levels, and prostate size, the serum PSA levels measured during hospitalization were significantly lower than those measured in the outpatient department in all subgroups, except in cases aged 20 to 39 years and those with PSA <4 ng/mL, in whom no significant differences were shown. Conclusions: Hospitalization decreases serum PSA values compared with those measured on an outpatient basis in patients with benign prostatic diseases. Therefore, serum PSA values should be checked on an outpatient basis for serial monitoring.
키워드
Hospital outpatient clinics; Hospitalization; Prostate-specific antigen
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