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Isolated Renal Mucormycosis in a Healthy Immunocompetent Patient: Atypical Presentation and Course

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Pahwa Mrinal, Pahwa Archna R., Girotra Mohit, Chawla Arun,
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 ( Pahwa Mrinal ) 
India Sir Ganga Ram Hospital Department of Urology

 ( Pahwa Archna R. ) 
India Lady Harding Medical College Department of Pathology
 ( Girotra Mohit ) 
John Hopkins Institute
 ( Chawla Arun ) 
USA Hofstra North Shore-LIJ School of Medicine Department of Nephrology

Abstract


Isolated renal mucormycosis is rarely identified and has been described in only a handful of cases. We hereby report a case of isolated renal mucormycosis with an atypical presentation in an immunocompetent patient with no identifiable risk factors. A 30-year-old nondiabetic male presented with a poorly functioning right kidney with minimal constitutional symptoms. The patient underwent a right simple nephrectomy. Histopathology revealed necrotizing xanthogranulomatous pyelonephritis with mucormycosis. The postoperative period was uneventful and the patient was managed without any antifungal administration. We hereby emphasize that renal mucormycosis can affect immunocompetent healthy adults without any previously known risk factors and that asymptomatic patients with no evidence of fungemia or disseminated disease can be managed without administration of intravenous amphotericin.

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Amphotericin B; Immunocompetence; Mucormycosis; Urinary tract infection

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