Association between renal function, erectile function and coronary artery disease: Detection with coronary angiography
Canat Lutfi, Canat Masum, Guner Bayram, Gurbuz Cenk, Caskurlu Turhan,
소속 상세정보
( Canat Lutfi )
Turkey Kastamonu State Hospital Department of Urology
( Canat Masum )
Turkey Sisli Etfal Training and Research Hospital Department of Endocrinology
( Guner Bayram )
Hayri Sivrikaya Private Hospital Department of Urology
( Gurbuz Cenk )
Turkey Goztepe Training and Research Hospital Department of Urology
( Caskurlu Turhan )
Turkey Goztepe Training and Research Hospital Department of Urology
KMID : 0358320150560010076
Abstract
Purpose: Many patients admitted for acute myocardial infarction (AMI) have chronic renal insufficiency and erectile dysfunction (ED). This study aimed to evaluate the relationship between ED and the glomerular filtration rate (GFR) in patients with coronary artery disease.
Materials and Methods: We studied 183 patients undergoing coronary angiography owing to AMI. The GFR was calculated and the International Index of Erectile Function-5 (IIEF-5) was used to evaluate ED. The relations between erectile function, GFR, and the number of occluded coronary arteries were evaluated.
Results: Of 183 patients with a mean age of 55.2±11.16 years who underwent coronary angiography owing to AMI, 100 (54.64%) had ED. The ED rate was 45.36% (44/97) in patients with single-vessel disease, 64.5% (31/48) in patients with two-vessel disease, and 65.7% (25/38) in patients with three-vessel disease. The ED rate in patients with single-vessel disease was significantly lower than in the other groups (p<0.001). The mean IIEF scores were 24.2±4.3, 20.4±4.9, and 20.5±4.2 in the three groups, respectively (p<0.001). Mean GFRs were similar in patients with single-vessel disease, two-vessel disease, and three-vessel disease (128.2±46.8, 130.8±70.9, and 110.8±44.6, respectively, p=0.171). The GFR was significantly lower in the presence of ED only for single-vessel disease (p=0.001).
Conclusions: This study confirmed that the presence and severity of ED are linked to the number of occluded vessels as documented by coronary angiography. The presence of ED and reduced GFR are associated with single-vessel coronary artery disease. This relationship can be used to predict the likelihood of coronary artery disease.
키워드
Coronary artery disease; Erectile dysfunction; Glomerular filtration rate
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