주요 신경계질환의 항우울제 처방 패턴: 2017년 제도 변경 이전
Prescription Pattern of Antidepressants in Korea for Major Neurological Disorders: Before the Policy Change in 2017
박윤아, 백은선, 최지미, 이준영, 이수현, 박건우,
소속 상세정보
박윤아 ( Park Yoon-Ah )
고려대학교 안암병원 신경과
백은선 ( Baek Eun-Sun )
한국화이자제약
최지미 ( Choi Ji-Mi )
고려대학교 의과대학 의학통계학교실
이준영 ( Lee June-Young )
고려대학교 의과대학 의학통계학교실
이수현 ( Lee Su-Hyeon )
한국화이자제약
박건우 ( Park Kun-Woo )
고려대학교 안암병원 신경과
Abstract
Background: It is well known that patients with neurological disorders are vulnerable to depression. However, in Korea, National Health Insurance services had banned non-psychiatrists from prescribing antidepressants for more than 2 months until January 2017. Now, neurologists are able to prescribe antidepressants to patients with only four neurological disorders. Due to this recent change in national health insurance policy, there will be a large change in the prescription pattern of antidepressants. In this study, we performed an analysis of antidepressant prescription patterns in Korea prior to this recent policy change.
Methods: The source population of this retrospective cohort study is the Health Insurance Review & Assessment Service database. We analyzed the claim database for patients who have one of four major neurologic disorders and had healthcare documentation submitted by healthcare providers between January 1, 2011 and December 31, 2016.
Results: During 2012-2016, antidepressant prescription rates of 6.21% (127,192 of a total 2,048,165 patients), 9.93% (81,861 out of 824,290), 10.12% (173,582 of 1,714,776), and 13.36% (48,530 of 363,347) were found for cerebrovascular disease, epilepsy, dementia, and Parkinson’s disease respectively. The most frequently prescribed antidepressant in cerebrovascular disease and epilepsy was tricyclic antidepressants (TCAs). In Parkinson’s disease and dementia, the most frequently used antidepressant was selective serotonin reuptake inhibitors.
Conclusions: The overall prescription rate of antidepressants was much lower than the estimated rates reported in other countries. TCAs were the primarily prescribed antidepressant. It is now expected that TCAs will be replaced by newer antidepressants.
키워드
Depression; Antidepressive agents; Nervous system diseases
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