다계통위축 임상표현형으로 발현한 2형척수소뇌실조
A Patient with Spinocerebellar Ataxia 2 Presenting with Multiple System Atrophy
김용성, 이상진, 신혜원,
소속 상세정보
김용성 ( Kim Yong-Sung )
중앙대학교병원 신경과
이상진 ( Lee Sang-Jin )
중앙대학교병원 신경과
신혜원 ( Shin Hae-Won )
중앙대학교병원 신경과
Abstract
Spinocerebellar ataxia type-2 (SCA2) is an autosomal dominant cerebellar ataxia that occurs due to expanded CAG trinucleotide repeats in the ATXN2 gene. Clinical features of parkinsonism in SCA2 vary from phenotypes of levodopa-responsive parkinsonism to multiple system atrophy. We described a patient with SCA2 presenting typical clinical manifestations of multiple system atrophy-c type with levodopa responsive parkinsonism whose dopamine transporter (DAT) image showed atypically reduced DAT uptake in in the striatum.
키워드
Spinocerebellar ataxias; Multiple system atrophy
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