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Clinical Analysis of Sterotactic Brachytherapy with High-Activity Iridium-192 Sources for Treatment of Malignant Astrocytomas
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KMID : 0359819930220020252
Abstract
Interstitial irradiation using high-activity Iridium-192 sources was studied clinically to treat supratentorial malignant astrocytomas (including glioblastoma multifrome). As of 1988, in attempt to define the efficacy of this technique in
patients
with
more extensive disease, we treated patients less rigid selection criteria.
15 eligible patients have been approached and ten have accepted randomization for follow-up study over two years. Pathology was anaplastic astrocytoma in 5 patients, glioblastoma multiforme in 5 patients. Mean survival of patients treated with
this
procedure was 18.4 months. Continued investigation will determine which patient may benefit from this techique.
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