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³ú¼ö¸·Á¾ÀÇ ¿¹ÈÄ ÆÇÁ¤À» À§ÇÑ ºÐ¿­±â ¼¼Æ÷ÃøÁ¤¿¡ °üÇÑ ¿¬±¸ A Study of AgNORs(Argyrophilic Nucleolar Organizer Regions) on Prediction of the Prognosis on Intracranial Meningiomas

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Abstract


A silver staining technique was used in the study of nucleolar organizer regions (AgNORs) from the paraffin sections of 26 meningiomas. The specimens were divided into four groups as follows : benign (n=16), atypical (n=5), anaplastic or
malignant
(n=5)
and recurrent without atypical histological findings (n=2) groups, and the mean number of AgNORs in each group was 1.47¡¾0.27, 1.93¡¾0.24, 2.00¡¾0.27 and 1.49¡¾0.53 respectively. We noted that the mean number of AgNORs reflected the cellular
kinetics of
a tumor and was related to histological grade. There was no significant difference between non-recurrent & recurrent benign meningiomas and it was thought that the main cause of recurrence in benign meningiomas was not perhaps cell proliferation
but
incomplete surgical removal.

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