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BCNU-CDDP Continuous Infusion Chemotherapy in Recurrent Oligodendroglioma
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KMID : 0359819960250030540
Abstract
Eight patients with recurrent oligodendroglioma were treated with 1.3-bis (2-chloroethyl) nitrosourea(BCNU) and CDDP continuous infusion chemotherapy. They were 5 with benign oligodendrogliomas and 3 with anaplastic oligodendrogliomas. All the
reourrent
tumors had been treated with surgery and radiotherapy. Four patients had already received chemotherapy with ACNU. Seven of them showed response to continuous infusion chemotherapy. The time the response to progression was 15 to 67 weeks. No
severe
complication of the chemotherapy was found. In conclusion. BCNU-CDDP continuous infusion chemotherapy is an effective treatment modality in recurrent oligodendrogliomas.
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