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ÁßÁõ ³úµ¿¸Æ·ù ÆÄ¿­È¯ÀÚÀÇ Ä¡·á Management of Poor-grade Patients with Ruptured Intracranial Aneurysm

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Abstract

¼­ ·Ð
ÀǽÄÀÌ ÁÁÀº(good grade : Hunt & Hess Grade ¥°, ¥±, ¥²) ³úµ¿¸Æ·ù ÆÄ¿­ ȯÀÚÀÇ Ä¡·á´Â
Á¶±â¿¡ ÀçÃâÇ÷ÀÇ À§ÇèÀ» Á¦°ÅÇÑ ÈÄ ³úÇ÷°ü ¿¬ÃàÀÇ ¿¹¹æ ¹× Ä¡·á¸¦ Àû±ØÀûÀ¸·Î ÇÏ´Â °ÍÀ¸·Î
Á¤ÂøµÇ¾î °¡°í ÀÖÀ¸³ª Grade ¥³, ¥´¿¡ ÇØ´çµÇ´Â poor gradeȯÀÚÀÇ Ä¡·á Áöħ¿¡ ´ëÇؼ­´Â ³í
¶õÀÌ ¸¹´Ù. °ú°Å poor gradeȯÀÚÀÇ Ä¡·á´Â ¼ö¼ú °á°ú°¡ ȸÀÇÀûÀÌ°í Àç¿øÀÇ ³¶ºñ¶õ Ãø¸é¿¡¼­
ÀÏ´Ü º¸Á¸Àû Ä¡·á ÈÄ ÀÓ»ó °æ°ú¿¡ µû¶ó Àû±ØÀû Ä¡·á ¿©ºÎ¸¦ °áÁ¤ÇÏ´Â °ÍÀÌ ÀϹÝÀûÀ̾ú´Ù.
Á¶±â ¼ö¼úÀº Áö¿¬ ¼ö¼ú¿¡ ºñÇؼ­ ¼ö±â»ó ¾î·Æ°í ¼ö¼ú ÇÕº´ÁõÀÇ ¹ß»ý·üÀÌ ³ôÀ¸¸ç Àû±ØÀû Ä¡
·á¸¦ ÇÏ´õ¶óµµ °á±¹ »ýÁ¸À²°ú »çȸ º¹±Í À²ÀÌ Àû´Ù´Â Á¡ÀÌ Á¦±â µÇ¾î ¿Ô´Ù. ÀÌ·¯ÇÑ Ä¡·á ¹æ
ħ¿¡ µû¸¥ °á°ú 3.8%¡­18%ÀÇ favorable outcome°ú 57.4%¡­874%ÀÇ »ç¸Á·üÀÌ º¸°íµÇ¾ú´Ù.
ÃÖ±Ù µé¾î good grade ÇÑÀÚ¿¡ ´ëÇÑ Á¶±â ¼ö¼úÀÌ ¾çÈ£ÇÑ ¼ºÀûÀ» ¾ò±â ½ÃÀÛÇϸ鼭 poor
gradeÇÑÀÚ¿¡°Ôµµ Àû±ØÀû Ä¡·á°¡ ½ÃµµµÇ¾î ´Ù¼Ò Çâ»óµÈ Ä¡·á ¼ºÀûµéÀÌ º¸°íµÇ¾ú´Ù. ±×·¯³ª.
Àû±ØÀû Ä¡·á ´ë»óÀÇ ¼±Åðú Ä¡·á ¹æ¹ý¿¡ ´ëÇÏ¿©¼­´Â ÀúÀڵ鰣¿¡ ÀÌ°ßÀÌ ÀÖ¾ú´Ù. º» ¿¬±¸ÀÇ
¸ñÀûÀº poor gradeȯÀÚµéÀÇ Æ¯¼º ¹× µî±Þº° ÀÓ»ó °æ°ú¸¦ ÆľÇÇÏ°í ºÒ·®ÇÑ ¿¹ÈÄÀÇ ¿øÀÎÀ» ºÐ
¼®ÇÔÀ¸·Î¼­, Àû±ØÀû Ä¡·á·Î ±³Á¤µÉ ¼ö ÀÖ´Â ¿øÀÎÀ» ã¾Æ³»¾î poor grade ȯÀÚÀÇ Ä¡·á ÁöħÀ» Á¤¸³Çϴµ¥ ÀÖ´Ù.
#ÃÊ·Ï#
To formulate treatment strategies for poor-grade patients after aneurysmal
subarachnoid hemorrhage(SAH), medical records were analyzed for 166 patients who
were in Hunt and Hess grade ¥³ or ¥´ among 588 consecutive aneurysmal SAH patients
admitted during the past 5 years. Causes for unfavorable outcome(poor or dead) in these
166 patients were carefully evaluated to improve the management outcome.
Overall management results were favorable(good or fair) in 71(42.8%), and unfavorable
in 95(78 dead, 17 poor). Direct clipping was performed in 90 patients, and the surgical
results were favorable in 69(76.7%) and unfavorable in 21(23.3%). Surgery was not
performed in 76 patients because of moribund state on arrival in 41, neurological
deterioration due to rebleeding in 15, massive brain swelling in seven, serious medical
illness in five, severe delayed ischemic deficit in one, and massive cerebral infarction
following angiography in one, and refused surgery in six. Seven patients survived from
non-surgery group(2 fair, 5 poor).
Direct effects of aneurysm rupture(34.8%) and early rebleeding(34.8%) were the causes
of unfavorable outcome in grade ¥³ patients, while it was direct of aneurysm
rupture(91.8%) in grade ¥´ patients. It is suggested that since rebleeding is the only
preventable factor of unfavorable outcome, urgent management seems necessary to
prevent rebleeding, especially for grade ¥³ patients. Grade ¥³ patients should be treated
aggressively with direct clipping for non-complex aneurysms or for patients with
hematoma, and with coil embolization for complex aneurysms without hematoma.

Å°¿öµå

Ruptured intracranial aneurysm; Management outcome; Poor-grade patients; Rebleeding.;

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