전이성 뇌종양의 임상분석
Clinical Analysis of Metastatic Brain Tumors
소속 상세정보
문승명/Seung Myung Moon
고영초/고한승/김창현/이호국/안명수/오세문/최선길/황도윤/Young Cho Koh/Han Seung Koh/Chang Hyun Kim/Ho Kook Lee/Myung Soo Ahn/Sae Moon Oh/Sun Kil Choi/Do Yun Hwang
KMID : 0359819980270020198
Abstract
결론
본 연구에서는 전이성 뇌종양 환자의 예후 인자로서 치료방법에 따른 여명기간의 연장에
차이가 있는지를 알아보기 위해, 치료 후 여명기간과 치료전후의 KP score를 기준으로 하
였는데, 보존적 요법군에 비해 수술적 치료군에서 여명이 다소 증가하였고(P value 0.3305),
수술적 치료후의 KP score의 호전은 보존적 치료방법에 비해 매우 유의한 차이가 있었다(P
value : 0.0027)
#초록#
Several prognostic factors have been implicated in survival prolongation in patients
with metastatic brain tumors. Among these, surgery has been regarded as very
significant one with respect to life prolongation and improving the quality of survival in
such patients. From August 1982 through July 1996, a serious of 31 patients with
metastatic brain tumors among 785 patients with operated brain tumors, whose medical
records. X-rays and follow-ups were available, was studied retrospectively to evaluate
the beneficial effects of surgery. Despite the limitations inherent to the retrospective
study and limited number of patients, we divided these patients into two groups to find
out any statistical differences in terms of survival and quality of survival among them :
1) Conservative group(8 nonoperated patients + 5 patients with biopsy or partial
resection) ; 18. The quality of survival was assessed by Karnofsky performance(KP)
scale before and after each treatment. The survival of the patients in the surgical
treatment group was longer than the conservative treatment group(14.5 months/ 10
months), but this was not statistically significant(P value : 0.3305). However
improvement of quality of survival, in terms of KP scale. was significantly higher in the
surgical treatment group(P value : 0.0027).
Although confounded by the lack of controlled, randomized study limitations of
retrospective study, aggressive surgery can be regarded to the have a significant role in
improving the quality of survival in patients with metastatic brain tumors.
Metastatic tumor; Retrospective study; Survival prolongation Quality of survival; Karnofsky performance score.;
키워드
원문 및 링크아웃 정보
등재저널 정보