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°æµµ ¹× ÁßÅëµµ µÎºÎ ¼Õ»ó ȯÀÚ¿¡¼­ÀÇ ÀÎÁöÀ¯¹ßÀüÀ§ÀÇ ÀÇÀÇ Significance of Cognitive Evoked Potentials In Patients with Mild to Moderate Head Injury

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±Ç¿µÁØ/Young Jun Kwon ±è±¹±â/ÀÓ¿µÁø/±èżº/À̺À¾Ï/ÀÓ¾ð/Gook Ki Kim/Young Jin Lim/Tae Sung Kim/Bong Arm Rhee/Eon Leem

Abstract

°á·Ð
°æÈñ´ëÇб³ ÀÇ°ú´ëÇÐ ½Å°æ¿Ü°úÇб³½Ç¿¡¼­´Â 53¸íÀÇ °æµµ ¹× ÁߵÀÇ µÎºÎ¼Õ»óȯÀÚ¿¡¼­
ÀÎÁöÀ¯¹ßÀüÀ§¸¦ ½ÃÇàÇÏ¿© À̸¦ 59¸íÀÇ ºñ½ÁÇÑ ¿¬·ÉºÐÆ÷¸¦ °®´Â Á¤»ó´ëÁ¶±º°ú ºñ±³ÇÏ¿© ´ÙÀ½
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1) ÁߵÀÇ µÎºÎ¼Õ»ó±ºÀº °æµµÀÇ µÎºÎ¼Õ»ó±º¿¡ ºñÇØ À¯ÀÇÇÑ P3ÀÇ Àẹ±âÀÇ Áö¿¬ÀÌ ³ªÅ¸³µ
À¸³ª, °æµµÀÇ µÎºÎ¼Õ»ó±º¿¡¼­´Â ´ëÁ¶±º°ú ºñ±³ÇÏ¿© P3ÀÇ Àẹ±â¿ÍÁøÆøÀÇ À¯ÀÇÇÑ Â÷À̸¦ °ü
ÂûÇÒ ¼ö ¾ø¾ú´Ù
2) CT³ª MRI¿¡¼­ ÀÌ»ó¼Ò°ßÀ» º¸ÀÎ ±ºÀº ÀÌ»ó¼Ò°ßÀ» º¸ÀÌÁö ¾ÊÀº ±ºº¸´Ù P3ÀÇ Àẹ±â°¡ ÀÇ
¹Ì ÀÖ°Ô Áö¿¬µÇ¾î ÀÖ¾úÀ¸¸ç, ÀÌ»ó¼Ò°ßÀ» º¸ÀÌÁö ¾ÊÀº ±ºÀº ´ëÁ¶±º°ú ºñ±³ÇÏ¿© ÀÇ¹Ì ÀÖ´Â Àá
º¹±âÀÇ Áö¿¬°ú ÁøÆøÀÇ °¨¼Ò¸¦ º¸ÀÌ°í ÀÖ¾ú´Ù
3) ±âÁú¼º ³úÁõÈıºÀº ¿Ü»ó¼º±äÀåÀå¾Ö±ºº¸´Ù P3Àẹ±â°¡ ÀÇ¹Ì ÀÖ°Ô Áö¿¬µÇ¾î ÀÖ¾úÀ¸¸ç. ¿Ü
»ó¼º ±äÀåÀå¾Ö±ºÀº ´ëÁ¶±º°ú ºñ±³ÇÏ¿© ÀÇ¹Ì ÀÖ´Â Àẹ±âÀÇ Áö¿¬°ú ÁøÆøÀÇ °¨¼Ò¸¦ º¸ÀÌ°í ÀÖ
¾ú´Ù
4) ³úÆÄ°Ë»ç¼Ò°ßÀÇ ÀÌ»óÀ¯¹«¿Í P3 Àẹ±âÀÇ Áö¿¬¿©ºÎ¿ÍÀÇ »ó°ü°ü°è´Â ¾ø¾ú´Ù.
À§ÀÇ °á°ú¸¦ Á¾ÇÕÇغ¸¾ÒÀ» ¶§ ÀÎÁöÀ¯¹ßÀüÀ§°¡ ¿Ü»óÁ¤µµ ¹× Àå¾ÖÁ¤µµÀÇ ÆÇÁ¤¿¡ ÀÖ¾î ±×°£
½ÃÇàÇØ¿Ô´ø °Ë»ç¿Í ÇÔ²² °´°üÀûÀÎ Æò°¡ÀÚ·á·Î¼­ ÀÌ¿ëµÉ ¼ö ÀÖÀ½À» º¸ÀÌ´Â °ÍÀ¸·Î »ç·áµÇ¸ç
ÇâÈÄ º¸´Ù ´õ ´Ù¾çÇÑ Áúº´±º¿¡¼­ÀÇ ÀÓ»óÀû¿ë ¹× ¿¬±¸°¡ ÇÊ¿äÇϸ®¶ó »ý°¢µÈ´Ù.
#ÃÊ·Ï#
Cognitive evoked potential(CEP) is the result of endogenous brain response following
cognitive stimulus. Only P3 wave is widely applicated in clinical fields among several
kinds of waves. We examined the CEP in 53 patients with mild to moderate head injury
and 59 control subjects for evaluation of the relationship between P3 finding and head
injury with respect to severity of head injury. CT or MRI finding, psychometric
diagnosis, and EEG findings.
The results are following ;
1) The patients with moderate head injury had significant prolongation of P3 latency
compared with mild head injured patients. However there was no statistical difference in
latencies and amplitudes between mild head injured patients and controls.
2) The patients with abnormal CT or MRI findings had significant prolongation of P3
latency compared with the patients with normal finding, And the patients with normal
finding displayed significant abnormalities of the P3 latency and amplitude compared
with normal controls.
3) The patients with organic brain syndrome had significant prolongation of P3 latency
compared with the patients with post-traumatic stress disorder. And the patients with
post-traumatic stress disorder displayed significant abnormalities of the P3 latency and
amplitude compared with normal controls.
4) Abnormalities of electroencephalogram were not correlated with pronlongation of P3
latencies.
On the basis of these data, we conclude that cognitive evoked potential can be used
as an objective index of cognitive function in patients with mild to moderate head
injury.

Å°¿öµå

Cognitive evoked potential; P3 wave; Latency Head injury.;

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