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Abstract

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°¡ ³úµ¿¸Æ·ù ÆÄ¿­¿¡¼­ Áß¿äÇÑ ¼ÒÀÎ ÀÎÀÚ·Î ÀÛ¿ëÇÑ´Ù. ³×°, ³úµ¿¸Æ·ù ÆÄ¿­Àº ±âÈÄÀÇ º¯È­¿Í
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#ÃÊ·Ï#
Seasonal and climatic variations have been linked to the occurrence of some types of
cerebrovascular disease. However, the conditions that lead to intracranial aneurysm
rupture are not known.
The purpose of the present study was to determine whether predisposing factors are
more related to intracranial aneurysm rupture and to determine relation of the stressful
condition to intracranial aneurysm rupture. In order to determine the predisposing
factors, the authors have examined the relationship between seasonal variation and
predisposing factors of cerebral aneurysm. The author investigated activites of the
patients and events as well as diurnal and seasonal variations in the onset of
subarachnoid hemorrhage(SAH) in 336 consecutive patients. The results showed that the
onset of SAH was associated with working in 11.0%, defecation and/or urination in
8.3%, sleeping in 6.9% and 4.2% walking. Hypertensive patients in aneurysmal rupture
was 36.0%. Subarachnoid hemorrhage occurred during stressful events in 36.3% of the
patients, during nonstreneous events in 34.8% and during rest or sleep in 9.8%. The
activities or events preceding subarachnoid hemorrhage were not known in the
remaining 18.8%. Men were more likely to have suffered their hemorrhages during
stressful events than women(47% vs 30%). Peak times of intracranial aneurysm rupture
usually occurred from 6 to 11 A.M.(36.0%) and from 4 to 6 P.M.(20.5%). The seasonal
variation of the onset of SAH showed the incidence to be slightly higher in winter than
in any other seasons.
We concluded that the occurrence of subarachnoid hemorrhage display seasonal and
diurnal variation. And the precipitation of aneurysmal rupture have two important factors
; increased arterial blood pressure and decreased cerebrospinal fluid pressure around the
aneurysm. Also, the onset of the subarachnoid hemorrhage is related to the physiological
circadian periodicity of blood pressure, climatic change and stressful events.

Subarachnoid hemorrhage; Circumstances; Seasonal and diurnal variation; Climatic change; Stressful events;

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