뇌종양의 진단에 Thallium-201 SPECT의 유용정 - 임상 분석 -
The Significance of Thallium-201 SPECT in the Diagnosis of Brain Tumors - Clinical Analysis -
소속 상세정보
강신혁/Shin Hyuk Kang
정용구/최재걸/이기찬/이훈갑/Yong Gu Chung/Jae Gol Choi/Ki Chan Lee/Hoon Kap Lee
KMID : 0359819980270081096
Abstract
결론
본 조사결과로 1) Thallium-201지표는 뇌종양의 악성도를 비교하는 데 의미가 있고
(p<0.05), 2) Thallium-201지표 1.5를 역치로 사용하였을 시 악성도에 따른 뇌종양의 정확도
(accuracy)는 82.5%이다 라는 결론을 얻었다. 따라서 이러한 Thallium-201 SPECT의 정량
분석은 뇌종양의 악성도에 따른 진단을 객관적으로 평가하는데 유용하게 이용될 수 있으리
라 생각되며 각 종앙별 비교, 종양의 재발 및 방사선 괴사 뇌경색 등에서의 Thallium-201
SPECT은 좀 더 비교조사가 필요하리라 생각된다
#초록#
Thallium-201 SPECT has shown varing uptakes in tumors, depending on their viability,
the type, and degree of malignancy. The authors analyzed Thallium-201 SPECT in brain
lesions quantitatively, to predict the degree of malignancy, to differentiate between high
and low grade astrocytic tumor by thallium uptake, and to differentiate radiation necrosis
from tumor recurrence. The thallium indices were 1.56+/-0.75 in the benign brain tumors
and 2.5+/-1.13 in the malignant brain tumors(P<0.05). There was differences in thallium
index between high(2.19+/-0.61) and low(1.87+/-0.81) grade astrocytic tumor, however it
was not statistically significant(p=0.05). The diagnostic accuracy of thallium index in
differentiating benign from malignant was 82.5% by a threshold of 1.5. The mean
thallium index of radiation necrosis and evaluation of brain tumors to predict the degree
of malignancy.
키워드
Thallium-201 SPECT; Brain tumors;
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