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Çѱ¹ÀÎ °á¸·Á¾¾çÀÇ º´¸®ÇÐÀû ºÐ·ù¿Í ºóµµ: ´ÜÀϱâ°ü ¿¬±¸ Pathological Classification and Incidence of Conjunctival Tumors in Korean Patients: Single-center Study

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ÀÌÁ¤¿ì ( Lee Jung-Woo ) 
¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇРõ¾Èº´¿ø ¾È°úÇб³½Ç

±è¼Ò¿µ ( Kim So-Young ) 
¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇРõ¾Èº´¿ø ¾È°úÇб³½Ç
Á¤¹®¼± ( Jung Moon-Sun ) 
¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇРõ¾Èº´¿ø ¾È°úÇб³½Ç

Abstract

¸ñÀû: Çѱ¹ÀÎ °á¸·¿¡ ¹ß»ýÇÑ Á¾¾çÀÇ º´¸®ÇÐÀû ºÐ·ù ¹× ¹ß»ý ºóµµ¿¡ ´ëÇÏ¿© ¾Ë¾Æº¸°íÀÚ ÇÑ´Ù.

´ë»ó°ú ¹æ¹ý: 2007³â 1¿ùºÎÅÍ 2016³â 12¿ù±îÁö ¼øõÇâ´ëÇб³ õ¾Èº´¿ø¿¡ ³»¿øÇÑ °á¸·Á¾¾ç ȯÀÚ Áß ÀýÁ¦ »ý°ËÀ» ½ÃÇà¹ÞÀº ȯÀÚ 234¸íÀÇ Àǹ«±â·ÏÀ» ÈÄÇâÀûÀ¸·Î ºÐ¼®ÇÏ¿´´Ù. °á¸·Á¾¾ç ȯÀÚÀÇ ³ªÀÌ, ¹ß»ý ºÎÀ§, »ö¼Ò ¿©ºÎ µîÀÇ ÀÓ»ó ¾ç»ó°ú Á¶Á÷ÇÐÀû ºÐ·ù¿Í ºóµµ¸¦ Á¶»çÇÏ¿´´Ù.

°á°ú: ÀýÁ¦ »ý°ËÀ» ¹ÞÀº 234¸íÀÇ Æò±Õ ³ªÀÌ´Â 37.9 ¡¾ 21.6¼¼¿´°í, ±¸°á¸·¿¡ ¹ß»ýÇÑ °æ¿ì°¡ 145¸í(62%)À¸·Î °¡Àå ¸¹¾Ò°í, »ö¼Ò¼º º´º¯À» º¸ÀÌ´Â °æ¿ì°¡ 68¸í(29.2%)À̾ú´Ù. ¾ç¼ºÁ¾¾çÀÌ 201¸í(85.9%), ¾Ç¼ºÁ¾¾çÀº 33¸í(14.1%)À̾ú´Ù. Á¶Á÷ÇÐÀû ºÐ·ù·Î´Â »óÇǼ¼Æ÷Á¾¾çÀÌ 71¸í(30.3%)·Î °¡Àå ÈçÇÏ¿´°í, Èæ»ö¼¼Æ÷Á¾¾çÀÌ 67¸í(28.6%), ¸²ÇÁ±¸¼º Á¾¾çÀÌ 34¸í(14.5%), Áö¹æÁ¾¾çÀÌ 26¸í(11.1%)ÀÇ ºóµµ¸¦ º¸¿´´Ù.

°á·Ð: Çѱ¹ÀÎÀÇ °á¸·Á¾¾çÀº ³ôÀº ºóµµ¿¡¼­ ¾ç¼ºÁ¾¾çÀÌ È®ÀεǾúÀ¸¸ç »óÇǼ¼Æ÷Á¾¾çÀÌ °¡Àå ÈçÇÏ¿´°í, ¼­¾çÀÎÀ» ´ë»óÀ¸·Î ÇÑ ¿¬±¸¿Í ´Þ¸® Èæ»ö¼¼Æ÷Á¾¾çÀÌ Àû¾ú´Ù. ÇÏÁö¸¸ ÀÓ»óÀûÀ¸·Î ¾Ç¼ºÀ» º¸ÀÌ´Â °æ¿ìµµ 14.1%·Î µå¹°Áö ¾Ê¾Æ ƯÈ÷ ȯÀÚÀÇ ³ªÀÌ°¡ ¸¹°í, °á¸·³¶¿¡ Å« Á¾¾çÀÌ »ý°åÀ» °æ¿ì ¾Ç¼ºÀÇ °¡´É¼ºÀÌ ³ôÀ¸¹Ç·Î Á¶Á÷°Ë»ç¸¦ ÅëÇØ Á¤È®ÇÑ Áø´Ü°ú Ä¡·á°¡ ÇÊ¿äÇÏ´Ù.

Purpose: To report the pathological classification and incidence of conjunctival tumors in Korean patients.

Methods: A retrospective chart review was conducted for 234 patients who underwent excisional biopsy of conjunctival neoplasia between January 2007 and December 2016 at Soonchunhyang University Hospital. The clinical features, histological classification, and frequency of pigmented conjunctival masses were investigated.

Results: The mean age of the 234 patients who underwent excisional biopsy was 37.9 ¡¾ 21.6 years. The most common location of conjunctival lesions was the bulbar conjunctiva in 145 patients (62%), with pigmentary lesions in 68 patients (29.2%). Most tumors were benign (n = 201, 85.9%), while 34 malignant tumors were found as follows: 71 patients (30.3%) had epithelial tumors, 67 (28.6%) had melanocytic tumors, 33 (14.1%) had lymphoid tumors, and 26 (11.1%) had lipomatous tumors.

Conclusions: Most of the conjunctival tumors in Korean patients were benign. Epithelial tumors were the most common, and melanocytic tumors were less common then in Western studies. However, clinically malignant cases were not uncommon, occurring at a rate of 14.1%. Therefore, conjunctival tumors in elderly patients, lesions that are large, and the presence of a conjunctival sac are more likely to be malignant. Therefore, accurate histological diagnosis and treatment are needed.

Å°¿öµå

Conjunctival neoplasms; Lymphoma; Pathology; Pigmented nevus; Squamous carcinoma

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