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¸Æ¶ô¸·½Å»ýÇ÷°üÀ» µ¿¹ÝÇÑ ½Ã½Å°æÀ¯µÎ µå·çÁ¨¿¡¼­ Ç×Ç÷°ü³»ÇǼ¼Æ÷¼ºÀåÀÎÀÚÁÖÀÔ¼ú Anti-Vascular Endothelial Growth Factor Therapy for Choroidal Neovascularization Secondary to Optic Nerve Head Druse

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¹Ú°¡Èñ ( Park Ka-Hee ) 
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Abstract

¸ñÀû: ½Ã½Å°æÀ¯µÎ µå·çÁ¨°ú ÀÌ¿¡ µ¿¹ÝµÈ ¸Æ¶ô¸·½Å»ýÇ÷°ü¿¡¼­ À¯¸®Ã¼°­ ³» Ç×Ç÷°ü³»ÇǼ¼Æ÷¼ºÀåÀÎÀÚ(º£¹Ù½ÃÁÖ¸¿)ÁÖÀÔ¼ú ½ÃÇà ÈÄ ¸Á¸·ÃâÇ÷ÀÇ °¨¼Ò ¹× ½Ã·ÂÈ£ÀüÀ» º¸ÀÎ Áõ·Ê¸¦ °æÇèÇÏ¿© À̸¦ º¸°íÇÏ°íÀÚ ÇÑ´Ù.

Áõ·Ê¿ä¾à: ±âÀúÁúȯÀÌ ¾ø´Â 53¼¼ ¿©ÀÚ°¡ °©ÀÛ½º·´°Ô ¹ß»ýÇÑ Á¾ÈÀÇ ½Ã·ÂÀúÇϸ¦ ÁÖ¼Ò·Î ³»¿øÇÏ¿´´Ù. ÃÖ´ë±³Á¤½Ã·Â ¿ì¾È 1.0, ÁÂ¾È 0.8, ¾È¾ÐÀº ¾ç¾È 15 mmHg·Î ÃøÁ¤µÇ¾ú°í ¼¼±Øµî°Ë»ç»ó Àü¾ÈºÎ¿¡¼­ ƯÀÌ ¼Ò°ßÀº °üÂûµÇÁö ¾Ê¾Ò´Ù. ¾ÈÀú°Ë»ç»ó Á¾ȿ¡ ¸Á¸·ÇÏÃâÇ÷ ¹× Àå¾×¼º ¸Á¸·¹Ú¸® ¼Ò°ßÀÌ °üÂûµÇ¾úÀ¸¸ç, Çü±¤¾ÈÀúÇ÷°üÁ¶¿µ ¹× Àεµ½Ã¾Æ´Ñ±×¸° Çü±¤¾ÈÀúÇ÷°üÁ¶¿µ°Ë»ç»ó ½Ã½Å°æÀ¯µÎ ±Ùó ºÎÀ§¿¡¼­ °úÇü±¤ºÎÀ§¸¦ È®ÀÎÇÏ¿´´Ù. ¾ç¾ÈÀÇ ½Ã½Å°æÀ¯µÎ µå·çÁ¨°ú Á¾ȿ¡ µ¿¹ÝµÈ ¸Æ¶ô¸·½Å»ýÇ÷°ü Áø´ÜÇÏ¿¡ À¯¸®Ã¼°­ ³» º£¹Ù½ÃÁÖ¸¿ÁÖÀÔ¼úÀ» ½ÃÇàÇÏ¿´°í 3ÁÖ ÈÄ ¸Á¸·ÃâÇ÷Àº È£ÀüµÇ´Â °æ°ú¸¦ º¸¿´´Ù.

°á·Ð: ½Ã½Å°æÀ¯µÎ µå·çÁ¨¿¡¼­ µ¿¹ÝµÈ ¸Æ¶ô¸·½Å»ýÇ÷°ü¿¡¼­ À¯¸®Ã¼°­ ³» Ç×Ç÷°ü³»ÇǼ¼Æ÷¼ºÀåÀÎÀÚ ÁÖÀÔ¼úÀÌ È¿°úÀûÀÎ Ä¡·á·Î °í·ÁµÉ ¼ö ÀÖÀ½À» º¸°íÇÏ´Â ¹ÙÀÌ´Ù.

Purpose: To describe a patient with optic nerve head drusen who showed improved retinal hemorrhage and visual acuity following intravitreal anti-vascular endothelial growth factor (bevacizumab) injection.

Case summary: A 53-year-old woman with no underlying disease presented with sudden vision loss in her left eye. Her best-corrected visual acuity was 1.0 in the right eye and 0.8 in the left eye; the intraocular pressure was 15 mmHg in both eyes. Anterior segment examination revealed no abnormal findings. Fundus examination showed subretinal hemorrhage and serous retinal detachment in the left eye. Fluorescein angiography and indocyanine green fundus examination revealed hyperfluorescence near the optic disc. The patient was diagnosed with choroidal neovascularization of the left eye secondary to optic nerve head drusen; intravitreal bevacizumab injection was then performed. Three weeks later, the patient showed improved retinal hemorrhage.

Conclusions: Intravitreal anti-vascular endothelial growth factor injection may be an effective treatment for choroidal neovascularization associated with optic nerve head drusen.

Å°¿öµå

Anti-vascular endothelial growth factor; Bevacizumab; Choroidal neovascularization; Intravitreal injection; Optic nerve head drusen

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