마이봄선기능장애 환자에서 안검미세각질제거의 임상효과
Clinical Efficacy of Microblepharoexfoliation in Meibomian Gland Dysfunction Patients
변형주, 전익현, 서경률, 김응권, 김태임,
소속 상세정보
변형주 ( Byeon Hyeong-Ju )
Yonsei University College of Medicine Department of Ophthalmology
전익현 ( Jun Ik-Hyun )
Yonsei University College of Medicine Department of Ophthalmology
서경률 ( Seo Kyoung-Yul )
Yonsei University College of Medicine Department of Ophthalmology
김응권 ( Kim Eung-Kweon )
Yonsei University College of Medicine Department of Ophthalmology
김태임 ( Kim Tae-Im )
Yonsei University College of Medicine Department of Ophthalmology
Abstract
Purpose: To assess the clinical efficacy of microblepharoexfolication using BlephEx™ (Scope Ophthalmics, London, UK) in meibomian gland dysfunction (MGD) patients.
Methods: We performed a prospective study involving 48 eyes of 24 patients who were diagnosed with MGD. All patients were treated with BlephEx™ for 8-10 minutes, and the ocular surface disease index (OSDI), tear break-up time (TBUT), Schirmer’s I test, corneal staining score, lid margin abnormality, MGD score, and lipid thickness layer using the Lipiview II (TearScience, Morrisville, NC, USA) were assessed before treatment and after one month.
Results: Significant changes were observed after microblepharoexfoliation using BlephExTM. The TBUT improved from 2.65 ± 1.16 to 3.77 ± 1.80 after 1 month (p < 0.001) and the OSDI improved from 38.83 ± 17.13 to 18.67 ± 15.01 after 1 month (p < 0.001). Before and after 1 month of treatment, the lid margin abnormalities were 2.98 ± 1.16 and 2.50 ± 1.01 (p < 0.001) and the MGD scores were 21.60 ± 6.95 and 18.02 ± 6.68 (p = 0.001), respectively.
Conclusions: BlephExTM improved the patients’ ocular surface symptoms, MGD score, and TBUT. Using steroid eye drops, there was a synergistic effect in improvement. Therefore, using BlephExTM may be suggested as a treatment option for MGD patients.
키워드
Biofilm; BlephExTM; Dry eye disease; Meibomian gland dysfunction; Microblepharoexfoliation
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