세포복제능력과 악성종양의 상관관계에 관한 연구
A Study on the Relationship beween Cellular Replicative Activity and Malignant Tumor
대한암학회지 1980년 12권 1호 p.101 ~ 105
소속 상세정보
엄승호/Um SH
이민철/이대일/Lee MC/LEE Dale
KMID : 0360319800120010101
Abstract
Every cell type has the capability of giving rise to cancer and, in general, the greater tbe replicative activity, the greater the cancer risk. However, there is neitber report on the extent of each cellular type of human body classified by cellular replicative activity, nor attempt to classify human malignant tumor by replicative activity of tissue of origin. The author tried to divide human body by 3 types of cell, so called, labile, stable and permanent cell, and calculated their percentage based on Forbes data on the gross composition of tbe adult body. And 1074 cases of malignant tumors diagnosed during 1976 1979 at Korea University Hospital were classified into labile, stable and permanent cell origin cancer based on replicative actvity of their tissue of origin. The data obtained are as following. l. Among tbe total cellular weight of adult human body, labile cells accounted for about 26%, and malignant tumors originated from this part occupied 83. 80% (900cases) of total 1074 cases. 2. Extent of stable cells in adult human body was about 14%, and percentage of malignant tumor from this part was 14.80%(159cases). 3. About 60% of adult human body was composed of permanant cells, but only 0. 37% (4cases) of malignant tumors were originated from this part. Above findings support the general knowledge.that the greater the replicative activity, the greater the cancer risk.
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