원발성간세포암의 진단에 있어서의 혈청 Ferritin 측정의 의의
Clinical Significance of Serum Ferritin Determination in the Diagnosis of Primary Hepatocellular Carcinoma
소속 상세정보
유재화/Ryu, Jae Hwa
양상호/박요한/구자영/박병채/Yang, Sang Ho/Park, Yo Han/Koo, Ja Young/Park, Byung Chae
KMID : 0360319860180010029
Abstract
In an attempt to verify the possibility that serum ferritin and serum ferritin/transaminases ratio might be an useful marker in the diagnosis of primary hepatocellular carcinoma, we checked serum ferritin level as well as serum ferritin/transaminases ratio in 52 patients with chronic liver diseases including primary hepatocellular carcinoma.
Serum ferritin level in patients with liver cirrhosis (281±4.83㎍/L, mean±SE) and with hepatocellular carcinoma(321±29.73 ㎍/L, mean±SE) were significantly(p<0.0005) elevated in comparison to normal control group(78.33±4.24 ㎍/L, mean±SE), but no statistical significance was observed between the patient groups of liver cirrhosis and hepatocellular carcinoma.
Moreover, we also failed to observe. a significant difference of serum ferritin/transaminases ratio in patients with liver cirrhosis (8.30±1.63, mean±SE) and with hepatocellular carcinoma(8.46±1.62, mean±SE).
The results of this study, therefore, would indicate that serum . ferritin determination seems to be not helful in the differential diagnosis of primary hepatocellular carcinoma.
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