암치료를 위한 RF 온열장치의 개발과 가온특성
Thermal Distribution and Development of RF Hyperthermia for Cancer Treatment
대한암학회지 1986년 18권 2호 p.183 ~ 193
추성길, 김귀언, 노준규, 김병수, 박민용, 양성화, 정동균,
소속 상세정보
추성길 ( )
연세대학교 의과대학 치료방사선과
김귀언 ( )
연세대학교 의과대학 치료방사선과
노준규 ( )
연세대학교 의과대학 치료방사선과
김병수 ( )
연세대학교 공과대학 전자공학과
박민용 ( )
연세대학교 공과대학 전자공학과
양성화 ( )
녹십자 의료공업주식회사
정동균 ( )
녹십자 의료공업주식회사
KMID : 0360319860180020183
Abstract
The biological effects for the use of hyperthermia to treat malignant tumors has been well studied and encouraging clinical results have been reported. However, the engineering and technical aspects of hyperthermia for the deep-seated tumors has not been satisfactory. We have developed the RF capacitive hyperthermia device (Greenytherm-GY 8) by cooperation with Yonsei Cancer Center and Green Cross Medical Corporation. It was composed with 8~10 MHz RF generator, capacitive electrode, matching system, cooling system, temperature measuring thermocouples and control PC computer. We, have measured the temperature and thermal distribution in agar phantom, animals and human tumors. This RF hyperthermia device could be applied for clinical trials as result of following studies.
1) The generating power could be varied to 700~1500 W
2) The Radio-frequency for capacitive heating could be produced to 8~10 MHz
3) It was possible to control the depth heating from skin by regulation the cooling temperature of bolus and choosing properly size electrodes.
4) Deep seated tumors (5~10 cm depth) might be heated to therapeutic temperature 40~43℃.
5) Side effects and hot feeling on skin could be significantly reduced by cooling bolus and electric matching.
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