임신과 합병된 유방암환자의 복합치료후 정상아 분만 1예
Normal Fetal Outcome after Multimodal Therapy for Breastr Carcinoma in the Early Second Trimester of Pregnancy
대한암학회지 1993년 25권 5호 p.780 ~ 784
소속 상세정보
박윤희
조삼현/김경태/황윤영/이재억/정파종
KMID : 0360319930250050780
Abstract
There were many papers stating that pregnancy had no deleterious effects to the management of the patients with malignant disease. But, it is well established that irradiation and cytotoxic drugs during pregnancy are associated with a significant
risk
of abortion and teratogenesis. These risks are concentrated in the first trimester and only minimal evidence of increased risk of malformation or abortion during the second or third trimester. We have experienced a normal fetal outcome from the
case of
a patient with an advanced, inflammatory breast cancer(stage III B) was diagnosed in the 2nd trimeter of the pregnancy.(18 weeks of gestation). Who was managed by 4 times of combination chemotherapy(5-FU; 500 mg/㎡. Adriamycin; 500 mg/㎡and
Cyclophospomide 500mg/㎡) and radiotherapy(total dose 6000 rad) from 19 weeks through 32 weeks of pregnancy.
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