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ÁøÇà ÃéÀå¾ÏȯÀÚ¿¡¼­ Ç×¾ÏÁ¦ ¹× ¹æ»ç¼±º´¿ëÄ¡·á¿Í ¿Â¿­Ä¡·áÀÇ È¿°ú Concurrent Chemoradiotherapy of Locally Advanced Pancreatic Carcinoma and Effects of Hyperthemia

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Abstract


The prognosis of pancreati cancer is still poor in spite of advance in surgical treatment and parasurgical adjuvant management.
Eighteen patients with histologically confirmed locally advanced adenocarcinoma of the pancreas were received radiation(5000cGy)+5-FU. Patients were treated with 5-FU 200mg/§³ IV bolus, 1 hour before irradiation each day. In some patients, within
30
minutes after radiotherapy, hyperthemia was added to above protocol two times weekly. Median survival of total patients was 9.5months. Median survival with RT+5-FU was 12.7 months from the date of treatment. Median survival with hyperthemia added
group
was 7.6months, but the survival difference was not significant statistically. The side effects were acceptable. There were no episodes of any life threatening toxicities.

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KoreaMed
KAMS