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À§¾ÏÀÇ ±ÙÄ¡¼ö¼ú ÈÄ¿¡ ÀüÀÌµÈ ¸²ÇÁÀýÀÇ °è·®Àû ºÐ¼® Quantitative Analysis of Metastatic Lymph Nodes after Curative Surgery in Gastric Cancer

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Abstract

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·Î 25%±îÁö´Â N1, ±×º¸´Ù ³ôÀ¸¸é N2·Î ±¸ºÐÇÏ´Â °ÍÀÌ À§Ä¡ °áÁ¤ÀÇ ¾î·Á¿ò ¾øÀÌ Á¤È®ÇÏ°Ô
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Purpose : A consecutive series of 710 patients who underwent curative gastrectomy
for carcinoma was studied with a special reference to the number or frequency of lymph
node metastasis and the patient's prognosis.
Material and Methods : Survival rates were calculated by the Kaplan-Meier method,
and the difference between each group was evaluated statistically by the log-rank
method. Follow-up was obtained for 709 patients(99.9%).
Results : According to the number of lymph nodal metastasis, the five year survival
rate for group 1(1¡­3 positive nodes) was 50.9%; for group 2(4¡­6 positive nodes),
56.7%; and for group 3(more than 6 positive nodes), 12.0%(p<0.0001). According to the
frequency of lymph node metastasis, the five year survival rate for those with up to 25
per cent frequency of metastasis was 47.5%; for those with up to 50 per cent frequency
of metastasis, 15.6%; and for those with greater than 50 per cent metastasis, 6.3%
(p<0.0001). According to the frequency of the regional lymph nodes(which include
perigastric nodes along the lesser and greater curvatures, nodes located along the left
gastric, common hepatic, splenic, and celiac arteries) metastasis, we categorized them as
group 0(N0: no metastasis), 1(N1 : metastasis in up to 25%), and 2(N2: metastasis in
greater than 25%).
Conclusion : This subdivision could be successfully applied to the clinical evaluation of
gastric carcinoma(five year survival rate for NO, 86.9%; for N1, 49.0%; and for N2,
10.7% (p<0.0001)) without difficulty in dividing certain lymph nodes into the correct
location.

Å°¿öµå

Staging of cancer; lymphadenectomy; Frequency of lymph node metastasis;

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