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Abstract

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#ÃÊ·Ï#
Cryptococcosis is a relatively common mycosis of human caused by a worldwide
Cryptococcus neoformans. Cryptococcosis occurs more frequently in
immuno-compromised hosts such as patients with lymphoma, AIDS, leukemia and other
debilitating diseases which manifest a condition of altered cell mediated immunity. Also
cancer patients with anticancer chemotherapy are at high risk. Cryptococcosis is
primarily a pulmonary disease that remains asymptomatic and unrecognised in most
cases. Meningitic and meningoencephalitc forms are more frequently diagnosed because
of their striking clinical symptoms. Meningoencephalitis is an uncommon form of
cryptoccocosis that often leads to coma and death within a short time, if it is not
quickly diagnosed and treated properly The treatment of choice for the cryptococcosis
consists of intravenous amphotericin B and 5-fluorocytocine. We report a case of
cryptococcal meningitis in 47-year-old female breast cancer patient with liver metastasis
after systemic chemotherapy. She complained headach, fever and diagnosed as
cryptococcal meningitis after the India ink smear and culture of CSF. After treated with
amphotericin B, her conditions were improved.

Å°¿öµå

Cryptococcus meningitis; Breast cancer;

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