유방암 500예의 임상적 고찰
A Clinical Study of 500 Cases of Breast Cancer
대한암학회지 1997년 29권 6호 p.1061 ~ 1068
박인식, 이미리나, 구자윤, 최승훈,
소속 상세정보
박인식 ( )
연세대학교 의과대학 외과학교실
이미리나 ( )
연세대학교 의과대학 병리학교실
구자윤 ( )
연세대학교 의과대학 외과학교실
최승훈 ( )
연세대학교 의과대학 외과학교실
KMID : 0360319970290061061
Abstract
결론
유방암의 호발연령군은 40대로 서구에 비하여 젊은 연령층의 비중이 높았다. 주증상은 종
괴의 촉지가 가장 많았으며 정기검진중 유방촬영이상으로 발견된 경우가 8.4%였다. Stage
Ⅰ, Ⅱ의 유방암에서 유방보존술이 점차 증가되어 33.6%로 높은 시행률을 보였고 변형 근치
적 유방 절제술이 52.8%였는데 양군간의 실제 생존율, 무병 생존율에는 통계적으로 유의한
차이가 없었다. 결론적으로 40대의 호발연령군에서 정기적인 검진이유 방암의 조기 발견에
도움이 될 것으로 생각되고 또한 초기 유방암에서 유방 보존술이 점차 증가 할 것으로 생각된다.
#초록#
Purpose : We investigated the clinical characteristics of breast cancers and its
significance.
Material and method : We evaluated the clinical characteristics of 500 women with
breast cancer who were diagnosed and treated by one surgeon between March 1991 and
August 1996.
Results : The median age was 46.7 years and the most common age group was 40's.
The presenting symptoms for most patients were palpable mass(75.2%) followed by
abnormal mammographic findings(8.4%), pain(6.3%) and nipple discharges(4.7%), and the
duration of symptoms was less than 1 month in 41.4%. Fifty three percent of the 500
cases had T2 lesion(size; 2 to 5 cm). With the increase of tumor size,
overall and disease free survival rates(OS, DFS) were decreased. Surgical treatment
consisted of modified radical mastectomy(52.8%) and partial mastectomy(33.6%) The
most common stage was Ⅱ(42.3%) and the early breast cancer(stage 0, Ⅰ, Ⅱ) was
388cases(78.1%) and the stage were inversely correlated with DFS and OS. The
positivity of axillary lymph node was 39.3% and the number of the metastatic lymph
nodes was inversely correlated with DFS and OS. The pathologic types were infiltrating
ductal carcinoma(83.0%), ductal carcinoma in situ(12.8%), infiltrating lobular
carcinoma(1.2%), lobular carcinoma in situ(0.4%) and Paget's disease(2.0%). ER
positivity was 48.9% and PR 46.9%. ER positive patients showed survival benefit
compared to ER negative patients. The common sites of distant metastases were lung,
bone and liver.
Conclusions : Our patients with breast cancer were younger than those of western
and showed the impacts on survival according to the lymph node status, tumor size.
키워드
Breast cancer; Clinical characteristics; Survival rates;
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