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À§¾ÏÀ¸·Î À§ÀüÀýÁ¦¼úÀ» ½ÃÇàÇÑ 329¿¹ÀÇ ÀÓ»óºÐ¼® ¿øÀڷº´¿ø ÀϹݿܰú Clinical Analysis of 329 Cases of Total Gastrectomy

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À̿켺/Woo Sung Lee ¹é³²¼±/¹®¼±¹Ì/³ë¿ìö/¹æÈ£À±/ÃÖµ¿¿í/ÀÌÁ¾ÀÎ/¹®³­¸ð/Nam Sun Paik/Sun Mi Moon/Woo Chul Noh/Ho Yoon Bang/Dong Wook Choi/Jong Inn Lee/Nan Mo Moon.

Abstract

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±¸¹Ì¿¡¼­´Â 1940³â´ëÀÌ·¡ À§¾ÏÀÇ ¹ß»ý ºóµµ ¹× ÀÌ·Î ÀÇÇÑ »ç¸Á·üÀÌ °¨¼ÒµÇ°í ÀÖÀ¸³ª, ¿ì
¸® ³ª¶ó ¿¡¼­´Â ¾ÆÁ÷µµ ¸ðµç ¾Ç¼º Á¾¾çÀÇ ¼öÀ§¸¦ Â÷ÁöÇÏ°í ÀÖ´Ù. ¶ÇÇÑ À§»óºÎ 1/3¿¡ ¹ß»ýÇÏ
´Â ±ÙÀ§ºÎ À§¾ÏÀÇ ¹ß»ýºóµµ´Â Àüü À§¾ÏÀÇ ¾à 15%¸¦ Â÷ÁöÇÏ°í ÀÖÀ¸¸ç ÃÖ±Ù »ó´ëÀûÀ¸·Î Áõ
°¡Ãß¼¼¿¡ ÀÖ´Ù.
À§¾ÏÀÇ Ä¡·á¹æ¹ýÀ¸·Î´Â ¼ö¼ú, Ç×¾Ï È­Çпä¹ý, ¹æ»ç¼±Ä¡·á, ¸é¿ª¿ä¹ý µîÀÌ ÀÖÀ¸³ª ÀÌÁß ¿Ï
Ä¡¸¦ ±â´ëÇÒ ¼ö ÀÖ´Â Ä¡·á¹ýÀº ¼ö¼úÀû ÀýÁ¦À̸ç, ÀÌ·¯ÇÑ À§¾Ï ¼ö¼úÀÇ ÃÖÁ¾ÀûÀÎ ¸ñÇ¥´Â ±ÙÄ¡
Àû ÀýÁ¦¼úÀ» ½ÃÇàÇÏ¿© Àç¹ßÀ» ÃÖ¼ÒÈ­ÇÏ°í »ýÁ¸À²À» Çâ»ó½ÃÅ´°ú µ¿½Ã¿¡, À§ ÀýÁ¦¼ú¿¡ µû¸£´Â
¿©·¯ °¡Áö ÇÕº´ÁõÀ» ÃÖ¼ÒÈ­ÇÏ°í, »îÀÇ ÁúÀ» Çâ»ó½ÃÅ°´Âµ¥ ÀÖ´Ù. ±¤¹üÀ§ÇÑ º´¼Ò ÀýÁ¦¿Í ÇÔ²²
D2 ¶Ç´Â D2+¥áÀÌ»óÀÇ ¸²ÇÁÀý °ûû¼úÀ» ½ÃÇàÇÏ´Â °ÍÀÌ ÇöÀç·Î¼­´Â ÃÖÀûÀÇ Ä¡·á¹ýÀ̸ç, À帷
À̳ª ¸²ÇÁÀý¿¡ ¾Ï¼¼Æ÷°¡ ħÀ±µÈ ȯÀÚ¿¡¼­´Â ¼ö¼úÈÄ º¸Á¶Àû Ç×¾Ï È­Çпä¹ý ¹× ¸é¿ª¿ä¹ýÀÌ ¿ä
±¸µÈ´Ù.
À§Ã¼ºÎ³ª À§ºÐ¹®ºÎ À§¾ÏÀº ´ëºÎºÐ À§ ÀüÀýÁ¦¼úÀÌ ¿ä±¸µÇ³ª ¼ö¼úÈÄ ÇÕº´Áõ ¹× »ç¸Á·üÀÌ À§
¾ÆÀü ÀýÁ¦¼úº¸´Ù ³ô°í, ƯÈ÷ ÁÖÀ§ Àå±âÀÇ º´ÇÕ ÀýÁ¦¼ú ½Ã¿¡´Â ´õ ³ôÀº À¯º´·ü°ú »ç¸Á·üÀ»
º¸À̹ǷΠÁ¤È®ÇÑ ÀûÀÀÁõ ÇÏ¿¡ ½ÃÇàµÇ¾î¾ß ÇÑ´Ù.
ÀÌ¿¡ ÀúÀÚµéÀº 1990³â 1¿ùºÎÅÍ 1993³â 12¿ù±îÁö ¿øÀڷº´¿ø ÀϹݿܰú¿¡¼­ À§¾ÏÀ¸·Î À§ Àü
ÀýÁ¦ ¼ú ¶Ç´Â À§ ÀüÀýÁ¦¼ú°ú º´ÇÕ ÀýÁ¦¸¦ ½ÃÇà ¹ÞÀº ȯÀÚ¿¡ ´ëÇØ ÀÓ»ó ºÐ¼®°ú ¾Æ¿ï·¯ »ýÁ¸
À²À» °áÁ¤ÇÏ´Â ÀÎÀڵ鿡 ´ëÇÏ¿© ÈÄÇâÀûÀÎ ºÐ¼®À» ½ÃÇàÇÏ°í, ¶ÇÇÑ »õ·Î¿î UICC º´±â ºÐ·ù¹ý
¿¡ µû¸¥ »ýÁ¸À²À» ºñ±³ÇØ º¸°íÀÚ ÇÏ¿´´Ù.

Purpose : This study was designed to evaluate the safety including the morbidity and
mortality of total gastrectomy and combined organ resection, to examine the survival
rate and the prognostic factors of gastric cancer following the total gastrectomy and to
assess the prognostic predictability of new UICC staging system after surgery in gastric
cancer patients.
Material and Method : To evaluate demographic features, clinical presentations,
preoperative diagnostic accuracy, postoperative complications and prognostic factors, we
analyzed 329 patients who underwent the total gastrectomy or the total gastrectomy
with combined resection for gastric malignancy at KCCH from Jan. 1990 to Dec. 1993
retrospectively.
Results : The early postoperative complication rates of overall patients and combined
resection group were 9.1% and 8.9% Mortality of these were 0.9% and 1.1%(p> 0.05).
The overall 5YSR was 52.8% and there was no significant differrence in the survival
rate between the total gastrectomy only group and the combined resection group. The
accuracy of preoperative UGIS and abdominal CT for determiantion of resectability were
over 80% . The depth of invasion and lymph node metastasis were independent
prognostic factors.
Conclusion : The total gastrectomy with combined resection should be considered
when indicated, because the postoperative morbidity and mortality is low and long term
survival is expected. The new UICC staging system seems to be good to predict
prognosis in gastric cancer patients.

Å°¿öµå

Stomach cancer; Total gastrectomy;

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