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35¼¼ ÀÌÇÏ ¿©¼ºÀÇ À¯¹æ¾Ï Breast Cancer of 35 Years old or Less

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Abstract

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°¡´É¼ºÀÌ ³ôÀ¸¹Ç·Î, 30¼¼ ÀÌÇÏÀÇ È¯ÀÚ, ƯÈ÷ 2º´±âÀÇ ¿©¼º¿¡¼­´Â Á» ´õ Àû±ØÀûÀÎ º¸Á¶È­ÇÐ
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Purpose : The age of onset of Korean breast carcinoma is younger than that in
western countries by some 10 years, thus the criteria of young age in manuscript from
western countries cannot reflect the characteristics of young breast cancer properly in
Korea.
Materials and Methods : We studied 290 breast cancer patients, 35 years old or
younger retrospectively, from Jan. 1980 to Dec. 1995 in the Department of Surgery,
Seoul National University Hospital. The age criteria of 30 and 35 years was utilized to
define two groups.
Results : The group(age 135) had larger primary tumors, more metastatic lymph
nodes, and worse stages than older counterpart(p=0.015, 0.0066, 0.0329 respectively).
They had worse disease-free survival but not overall survival(p=0.0312, 0.2427
respectively). The other group(age 130) showed significantly worse outcome in overall
as well as disease free survival(p=0.0056,0.0013) compared to the group(age>30). When
we compared the group of age¡Â30 to that of 31¡Âage¡Â35, there was statistically
significant difference in primary tumor size, axillary nodal status and pathological
stage(p=0.023, 0.019, 0.022 respectively).
Conclusion : The age of 30 might be better criteria to define young age as prognostic
factor rather than age of 35 in Korea.

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Age; Prognosis; Breast cancer;

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