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T1 À¯¹æ¾Ï¿¡¼­ ¾×¿Í¸²ÇÁÀýÀüÀÌÀÇ ¿¹Ãø The Prediction of Axillary Lymph Node Metastasis in T1 Breast Cancer

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Abstract

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Purpose : The axillary lymph node status is the most important prognostic factor in
breast cancer. The axillary node dissection is usually performed in infiltrating breast
cancer for the information of therapeutic decision and prediction of prognosis. But this
procedure may result in lymphedema of affected upper extremity nearly about 25%,
increased axillary drainage, sensory abnormality and pain. Many researches are focussed
to find the patients group who do not need axillary dissection according to the status of
tumor size, patient age, hormonal receptor and histologic grade.
Material and Methods : We evaluated the axillary lymph node status in patients with
tumor size less than 2 §¯ in diameter and thein correlation of other prognostic factor.
We reviewed 127 women with histologically diagnosed infiltrating ductal carcinoma of
breast who were treated by one surgeon at Yongdong Severance Hospital, Yonsei
University College of medicine between 1991 and 1996.
Results : Five patients (3.9%) had Tla lesion (<5 §®), 24 patients (18.9%) had Tlb
tumors (6¡­10 §®), and 98 cases (77.2%) had Tlc lesion (11¡­20 §®). The average
numbers of axillary lymph nodes dissected were 14.2. We found that smaller tumor size,
good histologic grade, estrogen receptor positivity, old age (over 50 years) showed a
tendency of decreased axillary node metastasis but without statistical significance.
Conclusion : There are possibility of finding subset with low risk of axillary lymph
node metastasis in small sized tumor with addition of good prognostic indicators such as
good histologic grade, hormonal receptors and old age.

Å°¿öµå

T1 breast cancer; Axillary lymph node metastasis;

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KoreaMed
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