유방 점액성 암(Mucinous Carcinoma)에 관한 임상적 고찰
Mucinous Carcinoma of the Breast -A clinical review-
대한암학회지 1999년 31권 1호 p.98 ~ 104
고승상, 이병찬, 梁在謨,
소속 상세정보
고승상 ( )
연세대학교 의과대학 외과학교실
이병찬 ( )
연세대학교 의과대학 외과학교실
梁在謨 ( )
연세대학교 의과대학 외과학교실
KMID : 0360319990310010098
Abstract
결론
우리나라 유방 점액성암의 임상적 특징은 비교적 외국의 보고와 비슷한 양상을 보이지만
몇 가지 부분에서는 차이를 보였다. 외국보다 젊은 여성에서 호발하였고(외국: 50대 이상,
우리나라: 40대), 2개월 미만의 증상발현기간과 만져지는 종괴를 주소로 가지는데 외국보다
증상발현기간이 짧았다. 또한 수술은 82.8%에서 변형근치적 절제술을 시행받고, 종괴의 크
기가 작고(2∼3 ㎝) 림프절 전이가 없는 낮은 병기(Ⅰ, Ⅱa)가 대다수를 차지한다. 단, 종괴
의 크기가 크며 병기가 높아지면 림프절전이나 원격전이의 빈도가 증가하였다. 호르몬 수용
체는 음성을 보이는 경우가 많았다.
#초록#
Purpose: Mucinous carcinoma of the breast is relatively rare among the malignant
breast lesions. It has distinctive pathological and behavioral characteristics to separate
from other types of breast cancers. According to the WHO definition, mucinous
carcinoma of the breast is a carcinoma containing large amounts of extracellular
epithelial mucus, sufficient to be visible grossly, and recognizable microscopically
surrounding and within tumor cells. Mucinous carcinoma shows the characteristic
features clinically and histologically because of the mucus production by the tumor.
Material and Methods: We reviewed 29 cases of mucinous carcinoma that had been
treated from 1985 to 1996 in the Department of General Surgery, Yonsei University
College of Medicine.
Results: The results were as follows: The prevalent age group was the fifth decade
(37.9%). The 27 cases were female and 2 were male. The most common sign and
symptom was a palpable mass (100%). The most patients visited the hospital within 2
months of onset (55.2%). Most frequent tumor size was 2∼3 ㎝ in diameter, found in 10
cases (34.5%), and 13.8% of cases was more than 5 ㎝ in diameter. The most frequent
site of tumor was the upper outer quadrant in 16 cases (55.2%). The operations
performed were as follows: Modified radical mastectomy (Auchincloss or Patey) in 24
cases (82.8%), quadrantectomy with axillary lymph node dissection in 4 cases (13.8%),
simple mastectomy with lower axillar dissection in 1 cases (3.4%). Axillary lymph node
metastasis was present in 3 cases (10.3%). The most common stage at diagnosis was
stage Ⅱa in 13 cases (44.8%).
Conclusion: This study shows some characteristics of mucinous carcinoma of breast
distinict from those previously proposed Further studies are needed to identify clinical
parameters which characterize mucinous carcinoma of the breast.
키워드
Breast cancer; Mucinous carcinoma; Clinical review;
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