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±â°üÁö Âû°ú¼ú ¹æ¹ý¿¡ µû¸¥ Æó¾ÏÀÇ Áø´ÜÀ² Â÷ÀÌ -ÀÌÅ»Çü Âû°ú¼ú°ú ºñÀÌÅ»Çü Âû°ú¼úÀÇ ºñ±³- Differences of Diagnostic Rate According to Technique of Bronchial Brush in the Diagnosis of Lung Cancer -A comparison of withdrawn and nonwithdrawn brush-

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Abstract

¼­·Ð
Æó¾ÏÀÇ Á¶Á÷ÇÐÀû Áø´Ü½Ã ±â°üÁö³»½Ã°æÀ» ÀÌ¿ëÇÑ ±âȯÁö ¼¼Ã´¼ú(washing) ¹× Âû°ú¼ú
(brush) ¼¼Æ÷Áø °Ë»ç´Â Á¶Á÷»ý°ËÀ» º¸¿ÏÇØ ÁÖ´Â ¿ªÇÒÀ» ÇÑ´Ù. Æó¾ÏÀ» Áø´ÜÇϱâ À§ÇÑ ±â°üÁö
Âû°ú¼úÀº ±¼°î¼º ±â°üÁö³»½Ã°æÀÌ µµÀԵDZâ ÀüÀÎ °æÁ÷¼º ±â°üÁö³»½Ã°æÀÌ ÀÓ»ó¿¡ ÀÌ¿ëµÇ´ø ½Ã
ÀýºÎÅÍ ½ÃÇàµÇ¾ú´Ù. ±¼°î¼º ±â°üÁö³»½Ã°æÀÌ ÀÌ¿ëµÇ¸é¼­ 4¡­5 ¼¼´ë ±â°üÁö, Áï ¼¼ºÐÀý ±â°üÁö
(subsegmental bronchus)±îÁö ½Ã¼úÀÚÀÇ ´«À¸·Î º´º¯À» Á÷Á¢ È®ÀÎÇÒ ¼ö ÀÖ°Ô µÊ¿¡ µû¶ó º´
º¯¿¡ ¼ÖÀ» Á¢±ÙÇÏ´Â °ÍÀÌ º¸´Ù ¿ëÀÌÇÏ°Ô µÇ¾úÀ¸¸ç, ±â°üÁö³»½Ã°æ»ó º´º¯ÀÌ º¸ÀÌÁö ¾Ê´Â ¸»
ÃÊÇü Æó¾Ï¿¡¼­µµ ±â°üÁö Âû°ú¼úÀº Á¶Á÷»ý°Ë ¹× ¼¼Ã´ ¼¼Æ÷Áø °Ë»ç¸¦ º¸¿ÏÇØÁÖ´Â Áß¿äÇÑ Áø´Ü
±â¼ú·Î ³Î¸® ½ÃÇàµÇ°í ÀÖ´Ù.
±â°üÁö³»½Ã°æ°Ë»ç´Â ±â¼úÀûÀÎ Ãø¸é¿¡¼­ ¸¹Àº ¹ßÀüÀÌ ÀÖ¾úÀ¸³ª Âû°ú¼ú ¹æ¹ý¿¡ ´ëÇؼ­´Â ¾Æ
Á÷ È®¸³µÈ ±âÁØÀÌ ¾ø´Â ½ÇÁ¤ÀÌ´Ù. Âû°ú¼úÀ» ½Ç½ÃÇÑ ´ÙÀ½¿¡ ±âµµ·ÎºÎÅÍ ¼ÖÀ» Á¦°ÅÇÏ´Â ¹æ¹ý
ÀÇ Ãø¸é¿¡¼­ º»´Ù¸é, ±â°üÁö³»½Ã°æÀ» ±âµµ³» º´º¯ ºÎÀ§¿¡ µÐ ä ±â°üÁö³»½Ã°æÀÇ ÀÛ¾÷Åë·Î
(working channel)¸¦ ÅëÇØ ¼ÖÀ» Á¦°ÅÇÏ´Â ÀÌÅ»Çü Âû°ú¼ú(withdrawn brushÀº ¼¼Æ÷¼öÀÇ °¨¼Ò
·Î ÀÎÇØ Æó¾ÏÀÇ Áø´ÜÀ²ÀÌ ³·¾ÆÁú ¿ì·Á°¡ ÀÖ¾î ±â°üÁö³»½Ã°æÀ» ¼Ö°ú ÇÔ²² Á¦°ÅÇÏ´Â ºñÀÌÅ»Çü
Âû°ú¼ú(nonwithdrawn brush)ÀÌ ÁÖ·Î ½ÃÇàµÇ¾îÁ® ¿Ô´Ù. ±×·¯³ª ºñÀÌÅ»Çü Âû°ú¼úÀº Âû°ú¼úÀ»
¹Ýº¹Çϰųª Á¶Á÷»ý°Ë µîÀÌ ÇÊ¿äÇÑ °æ¿ì ±â°üÁö³»½Ã°æÀ» ´Ù½Ã »ðÀÔÇØ¾ß Çϸç ÀÌ·Î ÀÎÇØ È¯ÀÚ
¿¡°Ô »ó´çÇÑ ºÎ´ãÀ» ÁØ´Ù.
ÀúÀÚµéÀº ¹Ù¶÷Á÷ÇÑ Âû°ú¼úÀÇ ¹æ¹ý¿¡ °üÇÑ ¿¬±¸ÀÇ ÀÏȯÀ¸·Î ÀÌÅ»Çü ¹× ºñÀÌÅ»Çü Âû°ú¼úÀ»
ÅëÇØ ¾ò¾îÁö´Â °ËüÀÇ ¼¼Æ÷Ãæ½Çµµ(cellularity)¿Í Æó¾Ï Áø´ÜÀ² Â÷À̸¦ Á¶»çÇÏ¿´´Ù.

Purpose : Brush cytology is one of useful methods for establishing a diagnosis of
lung cancer. There are two methods of retrieving the specimen of brush cytology. One
is to withdraw the brush through the working channel of the bronchoscope (withdrawn
brush) and the other is to withdraw the brush and bronchoscope as a unit, with brush
remaining protruded through the distal tip of the bronchoscope (nonwithdrawn brush).
We tried to compare two methods in the cellularity of the specimen and the diagnosis
of lung cancer.
Materials and Methods : Thirty-one patients with suspected lung cancer were studied
prospectively. The sequence of sampling (withdrawn or nonwithdrawn brush) was
assigned randomly. The specimens were interpreted by two cytopathologists about
cellularity and presence of recognizable malignant cells.
Results : Cellularity was significantly greater for nonwithdrawn brush (P<0.05). There
was no significant difference of diagnostic rate between both methods in the diagnosis
of lung cancer.
Conclusion : Withdrawing the brush through the bronchoscope decreases the
cellularity, but it does not affect the diagnostic rate for lung cancer.

Å°¿öµå

Lung cancer; Bronchial brush;

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