재발성 위암의 치료 성적에 관한 후향적 연구
Retrospective Analysis of Treatment Results of Recurrent Gastric Cancer
대한암학회지 2000년 32권 3호 p.506 ~ 515
이혁준, 조삼제, 양한광, 이건욱, 최국진, 김진복,
소속 상세정보
이혁준 ( Lee Hyuk-Joon )
서울대학교 의과대학 외과학교실
조삼제 ( Cho Sam-Je )
서울대학교 의과대학 외과학교실
양한광 ( Yang Han-Kwang )
서울대학교 의과대학 외과학교실
이건욱 ( Lee Kuhn-Uk )
서울대학교 의과대학 외과학교실
최국진 ( Choi Kook-Jin )
서울대학교 의과대학 외과학교실
김진복 ( Kim Jin-Pok )
서울대학교 의과대학 외과학교실
KMID : 0360320000320030506
Abstract
Purpose : Recurrent gastric cancer has a very poor prognosis due to its diagnostic difficulties, variant recurrence patterns and no effective treatment modalities. In this study, we retrospectively analyzed treatment results of the recurrent gastric cancer.
Materials and Methods :We reviewed 1,286 patients who had taken radical surgery for primary gastric cancers and were diagnosed to have recurrences of their primary diseases. According to the medical records, we retrospectively analyzed the gross features, histologic types and TNM stages of primary gastric cancers. The symptoms, diagnostic modalities, durations, recurrence pattern, treatments and prognoses of recurrent diseases were also reviewed.
Results :The median survival time of total recurrent gastric cancer patients was 6.8 months. Loco-regional and distant recurrences had better results than peritoneal and mixed recurrences (p<0.01). Curative resection of recurrent cancer was done in only 1.6% (18 cases in loco-regional recurrence and 4 cases in distant recurrence), but in these cases, significant survival gain (5 year survival rate: 30.5%) was found compared to other treatment modalities (p<0.01). In multivariate analysis, the type of first operation, TNM stage, duration till recurrence, recurrence pattern, and
treatment modality of recurrence were meaningful for the survival time after recurrence.
Conclusion :In selective cases, recurrent gastric cancer had an effective treatment modality and was expected to have prolonged survival. Therefore, a careful diagnosis and an active treatment of the patients who have the recurrent gastric cancers should be done, especially for the loco-regional recurrence.
키워드
Recurrence;Stomach neoplasm;
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