위선암의 재발 및 그 관련 인자
Recurrence of Gastric Adenocarcinoma and Its Relating Factors
대한암학회지 2000년 32권 6호 p.1007 ~ 1014
이선일, 민병욱, 엄준원, 김승주, 목영재,
소속 상세정보
이선일 ( Lee Sun-Il )
고려대학교 의과대학 외과학교실
민병욱 ( Min Byung-Wook )
고려대학교 의과대학 외과학교실
엄준원 ( Um Jun-Won )
고려대학교 의과대학 외과학교실
김승주 ( Kim Seung-Joo )
고려대학교 의과대학 외과학교실
목영재 ( Mok Young-Jae )
고려대학교 의과대학 외과학교실
KMID : 0360320000320061007
Abstract
Purpose :The purpose of this study is to analyze the mode of recurrence and it’s relating factors in gastric adenocarcinoma.
Materials and Methods :1,446 patients who had been undergone gastrectomy for gastric adenocarcinoma from September 1983 to December 1996 (Department of Surgery, Korea University) were studied (median follow-up was 2.9 years). Of them, 243 patients who had been proven recurrence were studied on recurrence mode and clinicopathological factors.
Results :The mean duration to recurrence was 22 months. The modes of recurrence were locoregional (30.0%), peritoneal (23.0%), hematogenous (19.3%) and distant lymph node metastasis (4.1%) in order. In 23.5%, more than 2 recurrent pattern were combined. Age, gross type, tumor size and stage were statistically significant to the mode of recurrence. The disease free survival was calculated: regional lymph node, number of lymph node, stage, and tumor emboli had statistical significance in all types of recurrence and in locoregional recurrence, tumor size was significant. Multivariate analysis showed that regional lymph node influenced the disease free survival period in all cases and tumor size in locoregional recurrence.
Conclusion :The number of positive regional lymph node and tumor size are important factors predicting the timing of recurrence after curative resection for gastric adenocarcinoma.
키워드
Stomach neoplasm;Recurrence;
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