충수돌기염으로 발현된 원발성 비호즈킨 림프종
A Case of Primary Non-Hodgkin’s Lymphoma Presented as Appendicitis
배종대, 정호근, 정기훈, 정병욱, 이창화, 박건욱, 나득영,
소속 상세정보
배종대 ( Bae Jong-Dae )
동국대학교 의과대학 외과학교실
정호근 ( Jung Ho-Keun )
동국대학교 의과대학 외과학교실
정기훈 ( Jung Ki-Hoon )
동국대학교 의과대학 외과학교실
정병욱 ( Jung Byeong-Wuk )
동국대학교 의과대학 외과학교실
이창화 ( Lee Chang-Hwa )
동국대학교 의과대학 내과학교실
박건욱 ( Park Keon-Uk )
동국대학교 의과대학 내과학교실
나득영 ( Nah Deuk-Young )
동국대학교 의과대학 내과학교실
KMID : 0371320010610060625
Abstract
Malignant lymphoma comprise 1∼4% of the malignant neoplasms of the gastrointestinal tract (GIT), although primary lymphoma of the appendix is exceedingly rare. Primary non-Hodgkin’s lymphoma (NHL) of the appendix reportedly represents 0.015% of all GIT lymphomas. Most cases of primary appendiceal lymphoma have presented with a clinical appearance of acute appendicitis. It is therefore difficult to diagnosis preoperatively. We report a case of primary NHL of the appendix in a 31 year-old female. Appendectomy was performed as a result of the clinical diagnosis of acute appendicitis, due to the rebound tenderness of McBurney’s point and a thickend appendiceal wall seen on abdominal ultrasonography. Microscopic examination demonstrated an atypical large lymphoid cell dispersed in a background of small lymphocytes. There were no invading tumor cells on the resection margin. Immunohistochemical studies revealed the large atypical cells stained with B cell marker (CD20), Bcl-6, Ki-67 and UCHL-1 (CD45R0). The post-operative work-up consisted of a CT scan of the abdomen and thorax, a bone marrow biopsy and a gastrofiberscope. These results were normal. No further treatment was recommended. The patient is now 12 months post-operative and doing well.
키워드
원발성 비호즈킨 림프종; 충수돌기; Appendix; Non-Hodgkin’s lymphoma; Diffuse large B-cell lymphoma;
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