대장·직장암의 간전이 병소에 대한 고주파 치료(Radiofrequency Ablation); 초기경험 보고
Radiofrequency Ablation of Hepatic Metastasis from Colorectal Cancer; EarlyExperience
민병소, 이강영, 박재균, 김남규, 이종태, 민진식,
소속 상세정보
민병소 ( Min Byung-Soh )
연세대학교 의과대학 외과학교실
이강영 ( Rhee Kang-Young )
연세대학교 의과대학 외과학교실
박재균 ( Park Jea-Kun )
연세대학교 의과대학 외과학교실
김남규 ( Kim Nam-Kyu )
연세대학교 의과대학 외과학교실
이종태 ( Lee Jong-Tae )
연세대학교 의과대학 방사선학교실
민진식 ( Min Jin-Sik )
연세대학교 의과대학 외과학교실
KMID : 0371320020620020145
Abstract
Purpose: The aim of this study is to describe the safety and efficacy
of radiofrequency ablation (RFA) in the treatment of unresectable liver
metastasis from colorectal cancer. Methods: From January 1999 to
December 2000, we undertook 48 RFA procedures in 36 patients with
unresectable metastatic liver tumor from colorectal cancer. RFA was
performed either via celiotomy (n=23) or using a percutaneous approach
(n=25) under ultrasound guidance using a LeVeen needle electrode and a RF
2000 generator. Patients were followed with spiral computed tomographic
scans at 1 week after RFA. Results: RFA was performed in 15 patients
with synchronous hepatic metastasis and 21 with metachronous hepatic
metastasis. The mean tumor size was 3.1 ㎝ (range; 0.5∼7.2 ㎝). In 2
patients, complete ablation failed due to anatomic tumor location. Nine
patients (25%) exhibited post RFA complications (9 cases of fever, 8 of
abdominal pain, and 1 of hematoma) which showed spontaneous resolution and
there was no treatment-related death. At a mean follow up of 10.1 months, 12
patients (33.3%) had recurred in the liver and 3 (8.6%) at the RFA site,
while 16 (44.4%) remained clinically free of disease. Conclusion:
Although RFA is a relatively safe procedure in patients with unresectable
hepatic metastasis from colorectal cancer, the possible development of new
metastatic disease after RFA is currently a limitation in this form of
treatment. Further study on the efficacy of RFA versus other treatment
modalities is needed.
키워드
대장암; 간전이; 고주파치료; Colorectal cancer; Hepatic metastasis; Radiofrequency ablation;
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