유방의 근상피세포암 1예
A Case of Myoepithelial Carcinoma of the Breast
신승용, 오세정, 박우찬, 김정수, 장은덕, 정상설,
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신승용 ( Shin Seung-Young )
가톨릭대학교 의과대학 외과학교실
오세정 ( Oh Se-Jeong )
가톨릭대학교 의과대학 외과학교실
박우찬 ( Park Woo-Chan )
가톨릭대학교 의과대학 외과학교실
김정수 ( Kim Jeong-Soo )
가톨릭대학교 의과대학 외과학교실
장은덕 ( Chang Eun-Deok )
가톨릭대학교 의과대학 임상병리학교실
정상설 ( Jung Sang-Seol )
가톨릭대학교 의과대학 외과학교실
KMID : 0371320020630010074
Abstract
A 42-year-old woman presented with a mass in the lower inner quadrant of the left breast that had been present for about 1 month. The mass was irregular in shape and rubbery in consistency, and measured 2×1.5 ㎝. It appeared well-demarcated, with
a
high density mass shadow on the mammogram. Lumpectomy was performed, with a 2 ㎝ safety margin surrounding the tumor mass, with simultaneous ipsilateral axillary dissection. The tumor was diagnosed from its histology and immunohistochemistry as a
myoepithelial carcinoma, in which the tumor cells were immunoreactive for the epithelial membrane antigen (EMA), smooth muscle actin and S-100 protein. These proteins are not specific to myoepithelial cells, but in combination, positive findings
indicate myoepithelial differentiation. Most myoepithelial tumors of the breast are benign. However, invasive breast tumors, showing myoepithelial cell differentiation, are rare and usually give rise to metastases. She had received postoperative
radiotherapy, and local recurrence and distant metastasis have not occurred so far. Here, we present a case of myoepithelial carcinoma of the breast, with a review of the literatures.
키워드
유방; 근상피세포암; Breast; Myoepithelial carcinoma;
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