유방에 발생한 낭포성 과분비성 관상피암 1예
Case of a Cystic Hypersecretory Duct Carcinoma of the Breast
소속 상세정보
이상철/Sang Chul Lee
김기환/안창혁/박우찬/오세정/김정수/전해명/유승진/정상설/임근우/Kee Hwan Kim/Chang Hyeok Ahn/Woo Chan Park/Se Jung Oh/Jeong Soo Kim/Hae Myung Jeon/Seung Jin Yoo/Sang Seul Jung/Keun Woo Lim
KMID : 0371320020630030247
Abstract
Breast cystic hypersecretory duct carcinomas (CHDC), characterized by cystic dilatation of ducts, cysts filled with thyroid colloid-like eosinophilic material, and by micropapillary carcinomas in the epithelium lining the cyst, is a rare
histological
variant of intraductal carcinomas. CHDC is differentiated from cystic hypersecretory hyperplasia. It's clinical manifestations are similar to those of other intraductal carcinomas. CHDC has a low-grade behavior for many years, but can be invasive,
with
the potential for metastasis. The importance of CHDC is its differentiation from a variety of other lesions of the breast, both benign and malignant. Various differential diagnoses for CHDC include: fibrocystic changes of the breast with
microcyst
formation, juvenile papillomatosis, benign mucocele-like lesions, juvenile secretory carcinomas, mucin-producing colloid carcinomas and metastatic follicular thyroid carcinomas. Histochemical staining (PAS, alcian blue & mucicarmine) or
immunoperoxidase
studies (CEA, alpha-lactalbumin and thyroglobulin) may also helpful in differential diagnoses. We report a case of a cystic hypersecretory duct carcinoma (CHDC) of the breast, and present a review of the literature.
키워드
유방암; 과분비성; 낭포성; Breast cancer; Hypersecretory; Cystic;
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