제 Ib 병기위암의 임상적 고찰
Clinical Analysis of Stage Ib Gastric Cancer
강석형, 류근원, 김승주, 목영재, 김종석, 구범환,
소속 상세정보
강석형 ( Kang Seok-Hyung )
국립암센터
류근원 ( Ryu Keun-Won )
국립암센터
김승주 ( Kim Seung-Joo )
고려대학교 의과대학 외과학교실
목영재 ( Mok Young-Jae )
고려대학교 의과대학 외과학교실
김종석 ( Kim Chong-Suk )
고려대학교 의과대학 외과학교실
구범환 ( Koo Bum-Hwan )
고려대학교 의과대학 외과학교실
KMID : 0371320020630040305
Abstract
Purpose: The aim of this study was to clarify the clinicopathological differences between T1N1M0 and T2N0M0, particularly the survival rates, and the role of chemotherapy in the stage Ib gastric cancer.
Methods: From January 1992 to December 1999, 118 cases were confirmed as having stage Ib gastric cancer in the Korea University Medical Center. Among them 31 patients were classified as being T1N1M0 and the other 87 cases were T2N0M0. The
clinicopathological features and the prognosis were evaluated retrospectively.
Results: The overall 5-year survival rate of the stage Ib gastric cancer patients was 94%. Overall 5-year survival rates in T1N1M0 and T2N0M0 were 100% and 91%, respectively. Though T1N1M0 group showed better prognosis, there was no
significant
difference between two groups (P=0.14). D1, D2, and D2+ α resections were performed in 28 cases (23.7%), 81 (68.6%), and 9 (7.6%), respectively, and there was no difference in the survival rate (P＞0.05). The 5-year survival rates were analyzed
according to whether or not they had received chemotherapy. There was a 98% 5-year survival rate with those who had chemotherapy and a 90% 5-year survival rate with those who had not had chemotherapy, but there was no significant difference between
them
(P=0.18). In the T2N0M0 group, the 5 year survival rates of patients with or without chemotherapy were 97% and 86%, respectively, but there was no significant difference (P=0.16).
Conclusion: Though T1N1M0 group showed a better prognosis than the T2N0M0 group, there was no significant difference between the two groups (P=0.14). There was no significant survival difference between D1, D2, or D2+ α procedures. It
appears
that post operative intravenous chemotherapy does not affect the prognosis of stage Ib gastric cancer, and the role of the chemotherapy in patients with T2N0M0 diseases is minimal.
키워드
항암요법; 임상병리학적 특성; 위암; 예후; 제 Ib 병기; Chemotherapy; Clinicopathologic feature; Gastric cancer; Prognosis; Stage Ib;
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