췌십이지장 절제술 후 발생한 가성동맥류 8예
Pseudoaneurysm after Pancreaticoduodenectomy Related with Delayed Massive Hemorrhages
문현종, 장원영, 허진석, 최성호, 조재원,
소속 상세정보
문현종 ( Moon Hyoun-Jong )
성균관대학교 의과대학 삼성서울병원 외과학교실
장원영 ( Chang Weon-Young )
성균관대학교 의과대학 삼성서울병원 외과
허진석 ( Heo Jin-Seok )
성균관대학교 의과대학 삼성서울병원 외과학교실
최성호 ( Choi Seong-Ho )
성균관대학교 의과대학 삼성서울병원 외과
조재원 ( Cho Jae-Won )
성균관대학교 의과대학 삼성서울병원 일반외과
KMID : 0371320020630040326
Abstract
Purose: Recently, hemorrhages has been accepted the most serious complication with a high mortality after a pancreaticoduodenectomy. In particular, delayed massive hemorrhages that occur from a pseudoaneurysmal rupture at the peripancreatic
large
arteries are quite formidable. In most patient with pseudoaneurysmal bleeding, sentinel hemorrhages can be observed. Early angiography and transcatheter arterial embolization can be used effectively as initial diagnostic and treatment modalities
for a
pseudoaneurysm. The authors reviewed the hemorrhagic complications from pseudoaneurysms after a pancreaticoduodenectomy and present the clinical features and treatment modalities.
Methods: Four hundred-fifty-four consecutive patients who underwent a pancreaticoduodenectomy between October 1994 and April 2002 were reviewed by a retrospective evaluation of their medical records. In 8 cases with hemorrhagic
complications,
pseudoaneurysms were determined by angiography to be the main cause of hemorrhage. The clinical characteristics, pre-hemorrhagic symptoms, treatments and outcomes were analyzed.
Results: Hemorrhagic complications occurred in 35 (7.7%) out of 454 cases of pancreaticoduodenectomy. In 8 (22.8%) out of 35 cases, the hemorrhage burst from the pseudoaneurysms. In 1 out of 8 cases, the hemorrhage originated from a
pseudoaneurysm on the proper hepatic artery, 1 case on the right hepatic artery, 1 case on the inferior pancreatoduodenal artery and on ligated gastroduodenal artery-stump in the remainder. Three cases had intra-abdominal complications such as a
pancreatic fistula. Sentinel bleeding were observed in 7 cases, bleeding from the surgical drains in 4 cases, hematemesis in 5 cases and melena in 1 case. In all cases, arterial embolization was attempted and 6 cases were successful. Two cases
required
surgery. There was 1 mortality from hepatic failure after the embolization.
Conclusion: Delayed massive hemorrhages after a pancreaticoduodenectomy should be ruled out when determining whether they are associated with an arterial pseudoaneurysmal rupture. Sentinel bleeding, which can be used as a warning sign of
pseudoaneurysmal rupture, can be detected with close observation. Transcatheter arterial embolization is an effective modality to control bleeding from an arterial pseudoaneurysm initially.
키워드
가성동맥류; 췌십이지장 절제술; 출혈; 동맥색전술; Pseudoaneurysm; Pancreatoduodenectomy; Hemorrhage; Transcatheter arterial embolization;
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