유방암에서 동결절편 조직검사의 유용성
Frozen Section Diagnosis of Breast Lesions
김형진, 박우찬, 박경신, 정상설,
소속 상세정보
김형진 ( Kim Hyung Jin )
가톨릭대학교 의과대학 외과학교실
박우찬 ( Park Woo-Chan )
가톨릭대학교 의과대학 외과학교실
박경신 ( Park Gyeong-Sin )
가톨릭대학교 의과대학 임상병리학교실
정상설 ( Jung Sang-Seol )
가톨릭대학교 의과대학 외과학교실
KMID : 0371320020630060445
Abstract
Purpose: Frozen sections of breast specimens can be used to determine malignancy in a suspected lesion of the breast during operation. However, this procedure always has a potential risk of reporting a false positive or negative. This study was performed to evaluate the accuracy of the frozen section diagnosis of breast lesions.
Methods:T A retrospective study to comparing the results of frozen and paraffin, section diagnosis was undertaken.
Results: 178 frozen breast section diagnoses were made between January 1995 and December 1996 at Kangnam St. Mary hospital. There were no false positive reports (0%) but 3 false negative reports (1.7%). The causes of a false negative were sampling error in 2 cases and interpretation error in the other. The sensitivity and specificity of the frozen section diagnosis were 94.5 and 99.2%, respectively.
Conclusion: Despite the high sensitivity and specificity of the breast specimen frozen section diagnosis, care should be taken when making a decision on the frozen section diagnosis due to the possibility of false negative results.
키워드
유방조직; 동결절편; 유방암
Breast; Frozen section; Breast cancer
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