위에서 발생한 원발성 융모암
Primary Gastric Choriocarcinoma
류승완, 김인호, 정철호,
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류승완 ( )
계명대학교 의과대학 외과학교실
김인호 ( )
계명대학교 의과대학 외과학교실
정철호 ( )
계명대학교 의과대학 외과학교실
KMID : 0371320030650040356
Abstract
A choriocarcinoma is a rapidly invasive, widely metastatic, human chorionic gonadotropin (HCG)-producing neoplasm, which are usually intrauterine and gestational. A primary gastric choriocarcinoma is very rare, and its pathogenesis is still uncertain. A 56-year old man presented with gastrointestinal bleeding and a gastric mass, clinically suspicious of a gastric adenocarcinoma. Thus, a radical subtotal gastrectomy a lmymph node dissection, with a reconstruction, was performed. The resected specimen was found to be a Borrmenn type Ⅰ tumor, and a histological examination showed it to be a primary gastric choriocarcinoma, with an associated adenocarcinoma and a syncytiotrophoblast, which was immunostained by human chorionic gonadotropin (HCG). The serum HCG level, on the 7^(th) postoperative day, was found to be 2,775 mlU/ml. Chemotherapy was administered two months after surgery, as the patient refused chemotherapy during the immediate post operative period. At that time, the tumor rapidly recurred and disseminated to the liver. The patient died three months after the initial diagnosis.
키워드
원발성 위융모암;Primary gastric choriocarcinoma
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