단순 유방촬영술상 발견된 미세석회화의 병리학적 결과
Pathologic Analysis of Clustered Microcalcification Found on Mammograms
강선희, 정기용, 김유사, 최진수, 이상숙,
소속 상세정보
강선희 ( Kang Sun-Hee )
계명대학교 의과대학 외과학교실
정기용 ( Chung Ki-Yong )
계명대학교 의과대학 외과학교실
김유사 ( Kim You-Sah )
계명대학교 의과대학 외과학교실
최진수 ( Choi Jin-Su )
계명대학교 의과대학 진단방사선과
이상숙 ( Lee Sang-Sook )
계명대학교 의과대학 병리학교실
KMID : 0371320040660010005
Abstract
Purpose: Clustered microcalcifications on mammogram represent an important feature of the breast cancer, especially that of intraductal carcinoma. The positive predictive value for malignancy of the clustered microcalcifications has been reported to be between 20 and 30%. This study was carried out te determine the radio-histological correlation of clustered microcalcifications seen on mammograms in a university hosipital in Daegu, Korea.
Methods: The medical records of 77 consecutive patients who underwent wire localization biopsy for clustered microcalcifications between January 1997 and March 2001 were reviewed. Patients with palpable mass in the breast were excluded. All of the mammograms were read by a single radiologist and interpreted as at least category 3 or above according to the American College of Radiology Breast Imaging Reporting and Data System (BIRADS). The localization was done using a J wire in the Diagnostic radiology department in the morning on the day of surgery. Removal of the clustered microcalcifications was confirmed in each case with specimen mammography.
Results: All patient were female, with mean age of 47.7 years old. There was no complication from the procedures. Excision of the microcalcifications was incomplete in four patients, giving the successful complete excision rate of 94.8%. Pathologic report showed malignancy in 29.9% consisting of ductal carcinoma in situ in 19.5% and invasive carcinoma in 10.4%. Only one of eight patients with invasive carcinoma had axillary lymph node involvement.
Conclusion: Needle localized surgical biopsy is safe, rapid, and accurate method for localizing small, potentially highly curable breast cancers with minimal sacrifice of breast tissue.
키워드
미세석회화;Needle localized open biopsy;Microcalcification
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